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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
CD210 (IL-10 R)
- 级别:
CD210 (IL-10 R) Antibody
- 目录编号:
CD210 (IL-10 R) Antibody
- 克隆性:
单克隆
- 抗原来源:
大鼠
- 保质期:
CD210 (IL-10 R) Antibody
- 抗体英文名:
Purified anti-mouse CD210 (IL-10 R) Antibody
- 抗体名:
CD210 (IL-10 R) Antibody
- 标记物:
CD210 (IL-10 R) Antibody
- 宿主:
大鼠
- 适应物种:
小鼠
- 免疫原:
CD210 (IL-10 R) Antibody
- 亚型:
CD210 (IL-10 R) Antibody
- 形态:
CD210 (IL-10 R) Antibody
- 应用范围:
FC, Block
- 保存条件:
2-8℃
- 浓度:
0.5 mg/ml
- 规格:
500 µg
Purified anti-mouse CD210 (IL-10 R) Antibody详细如下:
Description :CD210 is a 90-110 kD IL-10 receptor. It is a class II cytokine receptor expressed onthymocytes, T cells, B cells, NK cells, monocytes and macrophages. Ligand binding of CD210induces Jak1 and Tyk, resulting in STAT1 and STAT3 activation. IL-10 receptor stimulationresults in the inhibition of cytokine production and the costimulation of B cell proliferation anddifferentiation. The only known ligand for this receptor is IL-10.
Verified Reactivity :Mouse
Antibody Type :Monoclonal
Host Species :Rat
Immunogen :Soluble mIL-10R-FLAG-His
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation :The antibody was purified by affinity chromatography
Concentration :0.5 mg/ml
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C.
Application :FC - Quality tested、Block - Reported in the literature, not verified in house
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
Description :CD210 is a 90-110 kD IL-10 receptor. It is a class II cytokine receptor expressed onthymocytes, T cells, B cells, NK cells, monocytes and macrophages. Ligand binding of CD210induces Jak1 and Tyk, resulting in STAT1 and STAT3 activation. IL-10 receptor stimulationresults in the inhibition of cytokine production and the costimulation of B cell proliferation anddifferentiation. The only known ligand for this receptor is IL-10.
Verified Reactivity :Mouse
Antibody Type :Monoclonal
Host Species :Rat
Immunogen :Soluble mIL-10R-FLAG-His
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation :The antibody was purified by affinity chromatography
Concentration :0.5 mg/ml
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C.
Application :FC - Quality tested、Block - Reported in the literature, not verified in house
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation):
1. O'Farrell A, et al. 1998. EMBO J. 17:1006. (Block)
2. Wang W, et al. 2004. FASEB J. 18:1043. (Block)
3. Vieira PL, et al. 2004. J. Immunol. 172:5986. (Block)
4. Iwashiro M, et al. 2001. P. Natl. Acad. Sci. USA 98:9226. (Block)
5. Vicari AP, et al. 2002. J. Exp. Med. 196:541. (Block)
Product Citations:
1. Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
2. Sanctuary MR, et al. 2019. Mucosal Immunol. 0.638888889. PubMed
3. Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
4. Tanaka S, et al. 2018. J Exp Med. 215:1853. PubMed
5. Minshawi F, et al. 2020. Front Immunol. 11:1794. PubMed
6. He L, et al. 2018. Immunology. 153:84. PubMed
1. O'Farrell A, et al. 1998. EMBO J. 17:1006. (Block)
2. Wang W, et al. 2004. FASEB J. 18:1043. (Block)
3. Vieira PL, et al. 2004. J. Immunol. 172:5986. (Block)
4. Iwashiro M, et al. 2001. P. Natl. Acad. Sci. USA 98:9226. (Block)
5. Vicari AP, et al. 2002. J. Exp. Med. 196:541. (Block)
Product Citations:
1. Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
2. Sanctuary MR, et al. 2019. Mucosal Immunol. 0.638888889. PubMed
3. Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
4. Tanaka S, et al. 2018. J Exp Med. 215:1853. PubMed
5. Minshawi F, et al. 2020. Front Immunol. 11:1794. PubMed
6. He L, et al. 2018. Immunology. 153:84. PubMed
文献支持
Purified 抗小鼠 CD210 (IL-10 R) 抗体
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