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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
LOX-1
- 级别:
LOX-1 Antibody
- 目录编号:
LOX-1 Antibody
- 克隆性:
单克隆
- 抗原来源:
小鼠
- 保质期:
LOX-1 Antibody
- 抗体英文名:
Purified anti-human LOX-1 Antibody
- 抗体名:
LOX-1 Antibody
- 标记物:
LOX-1 Antibody
- 宿主:
小鼠
- 适应物种:
人
- 免疫原:
LOX-1 Antibody
- 亚型:
LOX-1 Antibody
- 形态:
LOX-1 Antibody
- 应用范围:
FC, IHC-F
- 保存条件:
2-8℃
- 浓度:
0.5 mg/ml
- 规格:
100 µg
Description :Lectin-like oxidized LDL receptor 1 (LOX-1) also known as CLEC8A is a 31 kD single pass typeII transmembrane protein and member of the C-type lectin superfamily. LOX-1 is a scavengerreceptor and is involved in endocytosis, phagocytosis and cytokine production. CLEC8A isexpressed by endothelial cells, smooth muscle cells, platelets, fibroblasts, macrophages, and isupregulated by inflammatory and oxidative stimuli. LOX-1 recognizes numerous ligandsincluding lipoproteins, apoptotic cells heat shock proteins, C-reactive protein and oxidized LDL.LOX-1 is implicated in atherosclerosis and vascular inflammation.
Verified Reactivity :Human
Antibody Type :Monoclonal
Host Species :Mouse
Immunogen :LOX-1 ectodomain: Fc fusion protein
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation :The antibody was purified by affinity chromatography.
Concentration :0.5 mg/m
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C.
Application :FC - Quality tested、IHC-F - Reported in the literature, not verified in house
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
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文献和实验1. Li D, et al. 2012. J. Exp. Med. 209:109. (IHC)
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