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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
CD206 (MMR) (Maxpar® Ready)
- 级别:
CD206 (MMR) (Maxpar® Ready) Antibody
- 目录编号:
CD206 (MMR) (Maxpar® Ready) Antibody
- 克隆性:
单克隆
- 抗原来源:
小鼠
- 保质期:
CD206 (MMR) (Maxpar® Ready) Antibody
- 抗体英文名:
Purified anti-human CD206 (MMR) (Maxpar® Ready) Antibody
- 抗体名:
CD206 (MMR) (Maxpar® Ready) Antibody
- 标记物:
CD206 (MMR) (Maxpar® Ready) Antibody
- 宿主:
小鼠
- 适应物种:
人
- 免疫原:
CD206 (MMR) (Maxpar® Ready) Antibody
- 亚型:
CD206 (MMR) (Maxpar® Ready) Antibody
- 形态:
CD206 (MMR) (Maxpar® Ready) Antibody
- 应用范围:
FC, CyTOF®
- 保存条件:
2-8℃
- 浓度:
1.0 mg/ml
- 规格:
100 µg
Description :Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known asCD206, MRC1, or mannose receptor (MR). It is a pattern recognition receptor (PRR) thatbelongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, andhepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range ofmicrobial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediatesendocytosis and phagocytosis, induces activation of macrophages and antigen presentation,plays an important role in host defense, and provides a link between innate and adaptiveimmunity.
Verified Reactivity :Human
Antibody Type :Monoclonal
Host Species :Mouse
Immunogen :Purified human mannose receptor
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA.
Preparation :The antibody was purified by affinity chromatography
Concentration :1.0 mg/ml
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C.
Application :FC - Quality tested、CyTOF® - Verified
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文献和实验1. Noorman F, et al. 1997. J. Leukocyte Biol. 61:63. (WB, IHC, Block)
2. Barrett-Bergshoeff M, et al. 1997. Thromb Haemost. 77:718. (Block)
3. Kato M, et al. 2007. J. Immunol. 179:6052. (IF)
Product Citations:
1. Alcántara‐Hernández M et al. 2017. Immunity. 47(6):1037-1050 . PubMed
2. Gide TN, et al. 2019. Cancer Cell. 35:238. PubMed
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