Brilliant Violet 605™ 抗人 CD184

Brilliant Violet 605™ anti-human CD184 (CXCR4) Antibody详细如下：

Description ：CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXCchemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and Tcells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets,lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons,among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates bloodcell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, bloodvessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and analternative receptor for some isolates of HIV-2.

Verified Reactivity ：Human, Cynomolgus, Rhesus

Reported Reactivity ：African Green, Baboon, Chimpanzee, Sooty Mangabey

Antibody Type ：Monoclonal

Host Species ：Mouse

Immunogen ：CP-MAC-infected Sup-T1 cells

Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).

Preparation ：The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 605™under optimal conditions.

Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)

Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.

Application ：FC - Quality tested

Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.

Brilliant Violet 605™ excites at 405 nm and emits at 603 nm. The bandpass filter 610/20 nm isrecommended for detection, although filter optimization may be required depending on otherfluorophores used. Be sure to verify that your cytometer configuration and software setupare appropriate for detecting this channel. Refer to your instrument manual or manufacturerfor support. Brilliant Violet 605™ is a trademark of Sirigen Group Ltd.

Excitation Laser ：Violet Laser (405 nm)