- ￥3700 - 7300
- 齐源
- 104725
- 国产/进口
- 2025年07月14日
- FC, IHC-F
- 仓鼠
- 小鼠
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
CD80
- 级别：
CD80 Antibody
- 目录编号：
CD80 Antibody
- 克隆性：
单克隆
- 抗原来源：
仓鼠
- 保质期：
CD80 Antibody
- 抗体英文名：
Brilliant Violet 421™ anti-mouse CD80 Antibody
- 抗体名：
CD80 Antibody
- 标记物：
CD80 Antibody
- 宿主：
仓鼠
- 适应物种：
小鼠
- 免疫原：
CD80 Antibody
- 亚型：
CD80 Antibody
- 形态：
CD80 Antibody
- 应用范围：
FC, IHC-F
- 保存条件：
2-8℃
- 浓度：
CD80 Antibody
- 规格：
125 µL/500 µL
| 规格： | 125 µL | 产品价格： | ￥3700.0 |
|---|---|---|---|
| 规格： | 500 µL | 产品价格： | ￥7300.0 |
Brilliant Violet 421™ anti-mouse CD80 Antibody详细如下：
Description ：CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is alsoknown as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells andmonocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation ofCD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendriticcells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cellactivation, proliferation, and cytokine production. CD80 appears to be expressed later in theimmune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliveran inhibitory signal to T cells.
Verified Reactivity ：Mouse
Reported Reactivity ：Dog
Antibody Type ：Monoclonal
Host Species ：Armenian Hamster
Immunogen ：CHO cell line transfected with mouse B7 (CD80)
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
Preparation ：The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™under optimal conditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested、IHC-F - Verified
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood. For immunohistochemical staining onfrozen tissue sections, the suggested use is 5-10 µg/mL. It is recommended that the reagent betitrated for optimal performance for each application.
Brilliant Violet 421™ excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50nm is recommended for detection. Brilliant Violet 421™ is a trademark of Sirigen Group Ltd.
Excitation Laser ：Violet Laser (405 nm)
Description ：CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is alsoknown as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells andmonocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation ofCD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendriticcells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cellactivation, proliferation, and cytokine production. CD80 appears to be expressed later in theimmune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliveran inhibitory signal to T cells.
Verified Reactivity ：Mouse
Reported Reactivity ：Dog
Antibody Type ：Monoclonal
Host Species ：Armenian Hamster
Immunogen ：CHO cell line transfected with mouse B7 (CD80)
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
Preparation ：The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™under optimal conditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested、IHC-F - Verified
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood. For immunohistochemical staining onfrozen tissue sections, the suggested use is 5-10 µg/mL. It is recommended that the reagent betitrated for optimal performance for each application.
Brilliant Violet 421™ excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50nm is recommended for detection. Brilliant Violet 421™ is a trademark of Sirigen Group Ltd.
Excitation Laser ：Violet Laser (405 nm)
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation)：
1. Harlan DM, et al. 1994. P. Natl. Acad. Sci. USA 91:3137. (IHC)
2. Razi-Wolf Z, et al. 1992. P. Natl. Acad. Sci. USA 89:4210. (Block, IP)
3. Hathcock KS, et al. 1994. J. Exp. Med. 180:631. (Block)
4. Herold KC, et al. 1997. J. Immunol. 158:984. (Block, IHC)
5. Ma XT, et al. 2006. Cancer Res. 66:1169.
6. Andoniou CE, et al. 2005. Nature Immunology 6:1011. (FC)
7. Lawson BR, et al. 2007. J. Immunol. 178:5366.
8. Turnquist HR, et al. 2007. J. Immunol. 178:7018.
9. Misra RS, et al. 2010. J. Exp Med. 207:1775. PubMed
10. del Rio ML, et al. 2011. Transpl. Int. 24:501. (FC) PubMed
11. Philipsen L, et al. 2013. Mol Cell Proteomics. 12:2551. PubMed
Product Citations：
1. Zenke S, et al. 2022. Nat Commun. 13:6459. PubMed
2. McNamara HA, et al. 2020. Cell Host Microbe. 572:28. PubMed
3. Chakrabarti J, et al. 2018. Oncotarget. 9:37439. PubMed
4. Go DM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:715. PubMed
5. White A, et al. 2014. J Immunol. 192:2659. PubMed
6. Super M, et al. 2021. Nat Biomed Eng. Online ahead of print. PubMed
7. Zenke S, et al. 2020. Immunity. 52(2):313-327. PubMed
8. Desanti G, et al. 2012. J Immunol. 189:5519. PubMed
9. Venturutti L, et al. 2020. Cell. 182(2):297-316.e27. PubMed
10. De Santi C, et al. 2022. Mol Ther Nucleic Acids. 29:643. PubMed
11. Cowan J, et al. 2014. J Immunol. 193:1204. PubMed
12. Abbott RK, et al. 2018. Immunity. 48:133. PubMed
1. Harlan DM, et al. 1994. P. Natl. Acad. Sci. USA 91:3137. (IHC)
2. Razi-Wolf Z, et al. 1992. P. Natl. Acad. Sci. USA 89:4210. (Block, IP)
3. Hathcock KS, et al. 1994. J. Exp. Med. 180:631. (Block)
4. Herold KC, et al. 1997. J. Immunol. 158:984. (Block, IHC)
5. Ma XT, et al. 2006. Cancer Res. 66:1169.
6. Andoniou CE, et al. 2005. Nature Immunology 6:1011. (FC)
7. Lawson BR, et al. 2007. J. Immunol. 178:5366.
8. Turnquist HR, et al. 2007. J. Immunol. 178:7018.
9. Misra RS, et al. 2010. J. Exp Med. 207:1775. PubMed
10. del Rio ML, et al. 2011. Transpl. Int. 24:501. (FC) PubMed
11. Philipsen L, et al. 2013. Mol Cell Proteomics. 12:2551. PubMed
Product Citations：
1. Zenke S, et al. 2022. Nat Commun. 13:6459. PubMed
2. McNamara HA, et al. 2020. Cell Host Microbe. 572:28. PubMed
3. Chakrabarti J, et al. 2018. Oncotarget. 9:37439. PubMed
4. Go DM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:715. PubMed
5. White A, et al. 2014. J Immunol. 192:2659. PubMed
6. Super M, et al. 2021. Nat Biomed Eng. Online ahead of print. PubMed
7. Zenke S, et al. 2020. Immunity. 52(2):313-327. PubMed
8. Desanti G, et al. 2012. J Immunol. 189:5519. PubMed
9. Venturutti L, et al. 2020. Cell. 182(2):297-316.e27. PubMed
10. De Santi C, et al. 2022. Mol Ther Nucleic Acids. 29:643. PubMed
11. Cowan J, et al. 2014. J Immunol. 193:1204. PubMed
12. Abbott RK, et al. 2018. Immunity. 48:133. PubMed
文献支持
Brilliant Violet 421™ 抗小鼠 CD80 抗体
￥3700 - 7300
