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文献和实验CDK Pathway: Cyclin-Dependent Kinases (cdks) and Cyclin-Dependent Kinase Inhibitors
In elucidating a novel cell-cycle pathway or mode of regulation, it will first be necessary to establish that the cell is arrested in a particular stage of the cell cycle following arrest-inducing conditions. This is achieved by staining
Cyclin-Dependent Kinase 5 (Cdk5): Preparation and Measurement of Kinase Activity
Cyclin-dependent kinase 5 (Cdk5) is a versatile protein kinase that plays a role in a variety of neuronal activities including neuronal migration during brain development, synaptic activities in mature neurons, and neuronal
Assays for Cyclin-Dependent Kinase Inhibitors
Cyclin-dependent kinases (CDK) are serine/threonine kinases that regulate cell cycle control and progression (1 ,2 ). A CDK holoenzyme complex is active if associated with its cyclin partner and if the complex is phosphorylated at specific
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