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- Biomatik
- 美国
- EKU03236
- 2025年07月06日
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文献和实验Antigen-presenting dendritic cells (DCs) originate from hematopoietic stem cells in bone marrow through successive steps of differentiation (1 -5 ). In peripheral tissues (e.g., skin), DCs are exposed to and capture antigens like viruses
of multipotent CD34+ CD45+ hematopoietic progenitors via employing hEB hematopoietic differentiation followed by adherent hemogenic endothelium generation. Multipotent hematopoietic progenitors can be reproducibly generated in robust amounts
and biochemical link between self-renewal and differentiation can now be experimentally approached using primary human cells. In addition, the models that result from these experiments are likely to generate highly relevant systems for use in identification
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