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文献和实验CpG 作为作为表观调控的重要组成部分，在基因调控方面起着重要作用。CpG 岛是什么，CpG 岛主要位于基因的启动子（promotor）和第一外显子区域，约有 60% 以上基因的启动子含有 CpG 岛。CpG 岛的 GC 含量大于 50%，长度超过 200bp。接下来介绍几个网站：EMBOSS、MethPrimer、Sequence Manipulation Suite。这三个网站的网址在对话框回复【0521】即可查询复制。这三个网站操作起来大同小异，EMBOSS 刚进入界面点击红色方框
Isolation of CpG Islands Using a Methyl-CpG Binding Column
Vertebrate genomes are globally heavily methylated at the sequence CpG, with the exception of short patches of GC-rich DNA of between 1–2 kb in size that are free of methylation, and these are known as CpG islands (see refs
Isolation of CpG Islands From BAC Clones Using a Methyl-CpG Binding Column
Vertebrate genomes are globally heavily methylated at the sequence CpG with the exception of short patches of GC-rich DNA, usually between 1–2 kb in size, which are free of methylation and these are known as CpG islands (see refs
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