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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
CD45.2
- 级别：
anti-mouse CD45.2 Antibody
- 目录编号：
anti-mouse CD45.2 Antibody
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
anti-mouse CD45.2 Antibody
- 抗体英文名：
PerCP/Cyanine5.5 anti-mouse CD45.2 Antibody
- 抗体名：
CD45.2 Antibody
- 标记物：
anti-mouse CD45.2 Antibody
- 宿主：
小鼠
- 适应物种：
小鼠
- 免疫原：
anti-mouse CD45.2 Antibody
- 亚型：
anti-mouse CD45.2 Antibody
- 形态：
anti-mouse CD45.2 Antibody
- 应用范围：
FC
- 保存条件：
2-8℃
- 浓度：
0.2 mg/ml
- 规格：
25 ug/100 ug
| 规格： | 25 ug | 产品价格： | ￥1400.0 |
|---|---|---|---|
| 规格： | 100 ug | 产品价格： | ￥4500.0 |
Description ：CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR,BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129).CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kDglycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets.There are multiple isoforms in the mouse that play key roles in TCR and BCR signaltransduction. These isoforms are very specific to the activation and maturation states of thecell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4,TCR, CD22, and Thy-1.
Verified Reactivity ：Mouse
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：B10.S mouse thymocytes and splenocytes
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography, and conjugated with PerCP/Cyanine5.5under optimal conditions.
Concentration ：0.2 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per millioncells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance foreach application.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.
Excitation Laser ：Blue Laser (488 nm)
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文献和实验1. Yakura H, et al. 1983. J. Exp. Med. 157:1077. (Block)
2. Yakura H, et al. 1986. J. Immunol. 136:2729. (Block)
3. Suzuki K, et al. 2000. Immunity 13:691. (IHC)
4. Shen FW, et al. 1986. Immunogenetics 24:146. (IP)
5. Baldwin TA and Hogquist KA. 2007. J. Immunol. 179:837.
6. Pascal V, et al. 2007. J. Immunol. 179:1751.
7. Burman AC, et al. 2007. Blood 110:1064.
8. Kincaid EZ, et al. 2007. J. Immunol. 179:3187.
9. Phan TG, et al. 2007. Nature Immunol. 8:992.
10. Nakano-Yokomizo T, et al. 2011. J. Exp Med. 208:1661. PubMed
11. Wen T, et al. 2013. PNAS. 110:6067. PubMed
12. Kohlmeier JE, et al. 2008. Immunity. 29:101. (FC) PubMed
Product Citations：
1. Charpentier JC, et al. 2020. Nat Commun. 11:180. PubMed
2. Dong MB, et al. 2020. Cell. 178(5):1189-1204.e23.. PubMed
3. Wang Y, et al. 2021. Cancer Res. 81:174. PubMed
4. Harsha Krovi S, et al. 2020. Nat Commun. 4.790277778. PubMed
5. Hirai T, et al. 2020. Immunity. 54(1):84-98.e5. PubMed
6. Viny AD, et al. 2019. Cell Stem Cell. 25:682. PubMed
7. Zhang LJ, et al. 2019. Immunity. 50:121. PubMed
8. Emal D, et al. 2016. J Am Soc Nephrol. 10.1681/ASN.2016030255. PubMed
9. Turner JS et al. 2018. Cell reports. 25(6):1395-1403 . PubMed
10. Stewart I et al. 2018. Immunity. 49(3):477-489 . PubMed
11. Fu B et al. 2017. Immunity. 47(6):1100-1113 . PubMed
12. Scalzo S, et al. 2022. Int J Nanomedicine. 17:2865. PubMed
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