Anti-CD19 CAR / NFAT (Lucifera
se) Reporter Jurkat Cell Line (CD19 SCFV-CD28-4-1BB-CD3ζ)- 询价
- BPS Bioscience
- 79853
- 美国
- 2025年12月22日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
1
- 供应商：
BPS Bioscience
- 细胞类型：
稳转细胞系
- 品系：
Jurkat
- 组织来源：
/
- 相关疾病：
多种
- 物种来源：
human
- 免疫类型：
多种
- 器官来源：
无
- 运输方式：
干冰
- 年限：
10
- 生长状态：
良好
- 英文名：
Anti-CD19 CAR / NFAT (Luciferase) Reporter Jurkat Cell Line (CD19 SCFV-CD28-4-1BB-CD3ζ)
- 规格：
2管
Anti-CD19 CAR consists of anti-CD19 scFv linked to 3rd generation CAR (Chimeric Antigen Receptor) containing CD28, 4-1BB co-stimulatory domains, and CD3ζ signaling domain.
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文献和实验• Predict the Mechanism of Action (MOA) of CAR.
• Intracellular co-stimulatory and activation
, as expected for direct regulation of the promoter. Those TFZF s that did not transactivate the promoter in the reporter assay (such as 144-4, 144-5, and 144-13) showed different activation profiles that varied depending on the cell line examined
, YWHAZ. Cell Cycle Proteins Regulated by the Erk1/2 Pathway: CCNA1, CCNA2, CCNB1, CCNB2, CCND1, CCND2, CCND3, CCNE1, CCNE2, CDK2, CDK4, CDK6, CDKN1A, CDKN1B, CDKN1C, CDKN2A, CDKN2B, CDKN2C, CDKN2D, E2F1, RB1. 2。T细胞与B细胞活化基因芯片 T细胞与B细胞活化基因芯片列有适应性免疫
哺乳动物RNAi技术 Mammalian RNA Interference
, which corresponds to 3 x 104 to 1 x 105 cells per well, depending on the cell line and its doubling time. PROTOCOL 4: COTRANSFECTION OF LUCIFERASE REPORTER PLASMIDS WITH SIRNA DUPLEXES Before siRNAs are applied to knock
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