BioLegend 504117 PE/Cyanine7 a

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BioLegend 504117 PE/Cyanine7 anti-mouse IL-4
产品简介：
产品品牌：BioLegend
产品货号：504117
产品名称：BioLegend 504117 PE/Cyanine7 anti-mouse IL-4
产品规格：25 µg

产品说明：
Clone  11B11 (See other available formats)
Regulatory Status  RUO
Other Names
Interleukin-4, Ia inducing factor (IaIF), B cell stimulating factor-1 (BSF-1), Hodgkin's cell growth factor (HCGF), Mast cell growth factor-2 (MCGF-2), Macrophage fusion factor (MFF), T cell growth factor-2 (TCGF-2)
Isotype  Rat IgG1, κ

描述
IL-4 是一种由活化的 T 细胞、肥大细胞和嗜碱性粒细胞产生的多效性细胞因子。IL-4是一种有效的淋巴细胞生长因子，可刺激某些B细胞和T细胞的生长和活化。IL-4 对辅助性 T 亚群发育的调控很重要。
IL-4 is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. IL-4 is a potent lymphoid cell growth factor which stimulates the growth and activation of certain B cells and T cells. IL-4 is important for regulation of T helper subset development.

Product Details
Isotype Control   PE/Cyanine7 Rat IgG1, κ Isotype Ctrl
Verified Reactivity  Mouse
Antibody Type  Monoclonal
Host Species  Rat
Immunogen  Partially purified native mouse IL-4
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation
The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration   0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application   ICFC - Quality tested

Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is =1.0 µg per million cells in 100 µl volume.  It is recommended that the reagent be titrated for optimal performance for each application.

Antigen Details
Structure   Cytokine; 15-19 kD (Mammalian)
Bioactivity
Differentiation of naïve CD4 T cells to the T+H2 type, proliferation/differentiation of activated B cells, expression of class II MHC antigens, and of low affinity IgE receptors in resting B cells
Cell Sources    Mast cells, T cells, bone marrow stromal cells
Cell Targets
B cells, T cells, monocytes, endothelial cells, fibroblasts
Receptors
Heterodimer IL-4Rα (CD124); γ-subunit (CD132) in common with IL-2R, IL-7R, IL-13R, IL-15R
Cell Type   Tregs
Biology Area   Immunology
Molecular Family    Cytokines/Chemokines

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