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- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Mesocricetus auratus CD27 antigen (Cd27), partial
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Mesocricetus auratus CD27 antigen (Cd27), partial品名简称:
Recombinant Mesocricetus auratus Cd27 protein, partial货号:
CSB-EP4836MRG规格:
20μg价格:
1344LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 90% as determined by SDS-PAGE.内毒素:
Not test生物活性:
/基因名:
Cd27Uniprot No.:
A0A3Q0DDP5别名:
/种属:
Mesocricetus auratus (Golden hamster)蛋白长度:
Partial来源:
E.coli分子量:
20.5 kDa表达区域:
21-187aa氨基酸序列:
TPASKSCPVRHYWTRGGLCCQLCKPGTFFVSDCSQNRTAALCEPCTPGVSFSPDFHTRPHCESCRHCNSGLLIRNCTIAANAECACSKGWQCRDQECTECDPPLNPALTTQPSVAPGPHPQPTHLPYAQEMAEARTVWPVHTRQFPASTLYNHWPSQRPLCSSDCVR蛋白标签:
N-terminal 6xHis-tagged and C-terminal Strep II-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
3-7 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
/功能2:
/文献:
1 RefSeq Submitted (APR-2022) to UniProtKB Cited for: IDENTIFICATION.研究领域:
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文献和实验Nature Medicine 再论多重免疫荧光揭示预测性生物标志物,用于优化免疫治疗临床试验设计
,这可以独立于 CD8+ T 细胞浸润水平来预测存活率。 使用转录组测序技术分析 TLS 阳性肉瘤对派姆单抗反应的决定因素 使用多重免疫荧光 (mIF) 分析显示,这类“高免疫”肉瘤的特征在于存在肿瘤内 TLSs. 三级淋巴结构(TLS)是 B 细胞滤泡、滤泡树突细胞 (DC) 和 CD4+ 和 CD8+ T 细胞的异位形成的聚集体,多项研究已证明其和抗癌免疫高度相关。 多重免疫荧光标记MUM1/CD20/CD27/CD3/COL1A1/IgG、CD8/GzmA/CD4/FOXP3/CD56分析TLS
该蛋白,比如P2X7;激活的P2X7会影响离子通道的转运从而影响下游信号通路,会对L-selectin(CD62L)和CD27进行剪切,导致细胞膜内的膜磷脂酰丝氨酸(PS)由脂膜内侧外翻,从而进入细胞早期凋亡阶段,这是经典的“NAD+诱导细胞凋亡”途径,或称为NICD,细胞因损伤而凋亡,最终获得细胞数量减少。由于获取细胞的实验过程中,需要对样本进行处理,不可避免的会对细胞造成一定的刺激,产生一定的细胞损伤。 Treg细胞的免疫抑制功能的研究一直是研究热点,但由于凋亡机制如“NAD+诱导
【进展|热点】nature medicine 最新研究表明一种具有干细胞特性的人记忆T细胞亚群
of lymphocytes capable of differentiating into effector cells in response to antigen re-exposure. Here we describe a long-lived human memory T cell population that has an enhanced capacity for self-renewal and a multipotent ability to derive central memory
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