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BMP4蛋白|人BMP4蛋白|人BMP4重组蛋白|Homo

sapiens BMP4 Recombinant Protein
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  • ¥1344 - 10872
  • CUSABIO已认证
  • CN
  • CSB-EP002740HUa0
  • 2025年07月13日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      -20℃/-80℃

    • 保质期

      Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

    • 英文名

      Recombinant Human Bone morphogenetic protein 4 (BMP4)

    • 库存

      200

    • 供应商

      武汉华美生物工程有限公司

    • 规格

      1mg/100ug/20ug

    规格:1mg产品价格:¥10872.0
    规格:100ug产品价格:¥2514.0
    规格:20ug产品价格:¥1344.0

    Research Areas

    Developmental Biology

    Uniprot ID

    P12644

    Gene Names

    BMP4

    Alternative Name(s)

    Bone morphogenetic protein 2B ;BMP-2B

    Lead Time

    3-7 business days

    Organism

    Homo sapiens (Human)

    Source

    E.coli

    Expression Region

    293-408aa

    Protein Length

    Full Length of Mature Protein

    Tag Info

    N-terminal 6xHis-tagged

    Target Protein Sequence

    SPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR

    MW

    15.4 kDa

    Purity

    Greater than 90% as determined by SDS-PAGE.

    Endotoxin

    Not test.

    Biological_Activity

    /

    Form

    Liquid or Lyophilized powder

    Buffer

    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

    Reconstitution

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

    Storage

    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

    Notes

    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

    Relevance

    Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during bryonic mammary development and to inhibit hair follicle induction .

    Function

    /

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    图标文献和实验
    该产品被引用文献
    Mutations in BMP4 are associated with subepithelial, microform, and overt cleft lip.Suzuki S., Marazita M.L., Cooper M.E., Miwa N., Hing A., Jugessur A., Natsume N., Shimozato K., Ohbayashi N., Suzuki Y., Niimi T., Minami K., Yamamoto M., Altannamar T.J., Erkhembaatar T., Furukawa H., Daack-Hirsch S., L'heureux J. , Brandon C.A., Weinberg S.M., Neiswanger K., Deleyiannis F.W., de Salamanca J.E., Vieira A.R., Lidral A.C., Martin J.F., Murray J.C.Am. J. Hum. Genet. 84:406-411(2009)
    相关实验
    • AAV 在肺部研究中的应用

      and mitophagy in lung fibroblasts 的研究论文。 该研究表明,骨形态发生蛋白 4  (BMP4) 在 人肺中的下调,在 IPF 疾病发生和进展中起 关键作用,BMP4 信号通路通过调节肺成 纤维细胞的衰老和线粒体自噬抑制肺纤维 化。因此,BMP4 信号的激活可能是治疗 IPF 肺纤维化的一种新型有效的治疗方法。 血清型:AAV9 注射方式:气管内注射 病毒滴度:1x1010 vp/ml 靶向部位:肺 动物模型:C57BL/6 BMP4+/+ and BMP4+/- mice

    • 玉米Proline responding 1(pro1)突变在蛋白合成和细胞周期调控中起到关键作用

      ),它是催化以谷氨酸为前体合成脯氨酸过程中的限速酶(Figure 2B, C, D, E)。Pro1基因功能的丧失,造成突变体中脯氨酸合成与积累的下降。Figure 2Phylogenetic Analysis of Pro1 and Biochemical Assay of Recombinant P5CS Protein.(A) Phylogenetic relationships of Pro1 (Zm P5CS) and its homologs.Maize Pro1 and identified

    图标技术资料

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    文献支持
    BMP4蛋白|人BMP4蛋白|人BMP4重组蛋白|Homo sapiens BMP4 Recombinant Protein
    ¥1344 - 10872