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- 2025年07月12日
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货期：电询
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MedChemExpress LLC
- CAS号：
2413865-92-4
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电询
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Antibacterial agent 83
CAS No. : 2413865-92-4
MCE 国际站：Antibacterial agent 83
产品活性：Antibacterial agent 83 (compound 17h) 对各种耐万古霉素 Enterococcus faecalis (VRE) 和耐甲氧西林 Staphylococcus aureus (MRSA) 显示出有效的抗菌活性。Antibacterial agent 83 可以显着减少 MRSA 的生物膜形成，并表现出良好的选择性。Antibacterial agent 83 在人肝微粒体中代谢稳定。
研究领域：Anti-infection
作用靶点：Bacterial
In Vitro: Antibacterial agent 83 (compound 17h) shows antibacterial activity against Newmana, USA300b, and Mu50, with MIC of 0.25 μg/mL all.
Antibacterial agent 83 performs poor stability in the liver microsomes of rat, mouse and dog.
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of concept in curing experimental infections. The second approach is based on screening for compounds with antibacterial activity and then employing a broad variety of newer technologies to identify the molecular target of the antibacterial agent
Methods to Assay Inhibitors of tRNA Synthetase Activity
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Assessing the Activity of Bacterial Multidrug Efflux Pumps
Resistance to antibiotics in target bacterial populations has long complicated antibacterial chemotherapy. First described in the early 1980s (1 , 2 ), efflux mechanism of resistance, whereby the antibiotic is actively (i.e., in an energy
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