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文献和实验Genomic Approaches to Antibacterial Discovery
of concept in curing experimental infections. The second approach is based on screening for compounds with antibacterial activity and then employing a broad variety of newer technologies to identify the molecular target of the antibacterial agent
Strategies for the Isolation and Characterization of Antibacterial Lantibiotics
. Because they bind to the key intermediate lipid II at a site not affected by clinically used antibiotics, they are effective against multidrug-resistant strains. We describe a bioassay-based method suitable for finding antibacterial lantibiotics from actinomycete
在制作切片或超薄切片时,由于组织是柔软的,或局部的软硬不均,这样制作厚薄均匀的切片是困难的。所以有必要用一定物质浸透组织内部,整个组织一样硬化,以利于切成薄片,这种物质叫做包埋剂。一股用光学显微镜观察的切片,用石蜡、火棉胶、炭蜡、明胶等作包埋剂;电子显微镜则用环氧树脂、聚苯乙烯树脂、异丁烯树脂及水溶性树脂。
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