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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
23635-14-5
- 规格：
10 mM * 1 mL/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥220.0 |
|---|---|---|---|
| 规格： | 50 mg | 产品价格： | ￥200.0 |
| 规格： | 100 mg | 产品价格： | ￥320.0 |
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(S)-(-)-Perillic acid
CAS No. : 23635-14-5
MCE 国际站：(S)-(-)-Perillic acid
产品活性：(S)-(-)-Perillic acid 是一种萜类植物提取物，具有抗菌和抗癌活性。(S)-(-)-Perillic acid 诱导细胞凋亡和细胞周期阻滞，增加细胞内 Bax，Bcl2，p21 和 caspase-3 的蛋白水平。(S)-(-)-Perillic acid 可用于癌症和感染研究。
研究领域：Apoptosis | Anti-infection
In Vitro: (S)-(-)-Perillic acid (1.0-3.5 mM; 24, 48 and 72 hours) time- and dose-dependently inhibits the growth of arterial smooth muscle cells (SMCs).
(S)-(-)-Perillic acid (1.0-3.5 mM; 20 hours) dose-dependently inhibits the nuclear incorporation of thymidine by rat SMC.
(S)-(-)-Perillic acid (2.5 mM; 24 hours) blocks cell cycle progression in G0/G1 interphase and induces apoptosis of SMCs.
(S)-(-)-Perillic acid (1.0-3.5 mM; 20 hours) dose-dependently inhibits [3H]FOH and [3H]GGOH incorporation into specific low molecular weight proteins.
(S)-(-)-Perillic acid (0.5 mM; 24 h) increases Bax, Bcl2, p21, and caspase-3 proteins in H520 cells.
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文献和实验Enzymatic Synthesis of (S)-Phenylalanine and Related (S)-Amino Acids by Phenylalanine Dehydrogenase
substituents in the reductive amination reaction. Optically pure (S)-phe and other (S)-amino acids are quantitatively synthesized from their oxo-analogs using PheDH, with a regeneration of NADH by formate dehydrogenase from Candida boidinii No. 2201. Acetone
have led to the conclusion that CYP2C19 is a major P450 responsible for (S)-mephenytoin 4’-hydroxylation activity in human liver microsomes (1 , 2 ). This is supported by the finding that cDNA-expressed CYP2C19 has a 50-to lOO-fold greater turnover number
A reverse-phase, high-performance liquid chromatography method is described for the quantification of 4′-hydroxymephenytoin formed enzymatically from 14 C-labeled (S )-mephenytoin following incubation with cDNA-expressed CYP2C19 or human
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