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- 文献和实验
- 技术资料
- 亚型:
IgG
- 形态:
液体
- 保存条件:
-20℃
- 克隆性:
多克隆
- 标记物:
无
- 适应物种:
HMR
- 保质期:
一年
- 抗原来源:
兔
- 供应商:
万类生物
- 宿主:
兔
- 应用范围:
WB
- 浓度:
>1 mg/ml
- 靶点:
CD86
- 抗体英文名:
CD86 antibody
- 抗体名:
CD86 抗体
- 规格:
50μl(>50μg)
产品概述
CD86 is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4.CTLA-4 shares 31% overall amino acid identity with CD28, and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counterreceptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.
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文献和实验CD86 分子 CD86 常用单克隆抗体或代号: FUN- 1,BU63,GR65;(B7- 2) 主要表达细胞: Ba,M [B] 分子质量(kDa)和结构: gp80(IgSF) 功 能: CD28、CTLA- 4配体,提供T细胞共刺激信号 CD86 Summary: Costimulates IL-2 production and T cell proliferation
Elabscience|巨噬细胞极化总失败?RAW264.7/THP-1/BMDM/hMDM四大模型避坑指南与实操全攻略
2. Raw264.7细胞M1极化检测结果 使用M1型Raw264.7巨噬细胞极化培养和检测试剂盒(XJM004)检测并分析结果,由图可见与无处理的Control组细胞相比,M1型巨噬细胞有短而密的伪足,细胞质内颗粒感明显增加,流式检测高表达F4/80、CD11b、CD86。 注意事项: (1)M1型诱导最佳条件:2.5×105个/mL细胞铺板,培养基条件为:DMEM高糖培养基+20%灭活血清+双抗,加入含LPS (300 ng/mL) + IFN-γ (200 ng/mL),诱导48 h
Topical Application of siRNA Targeting Cutaneous Dendritic Cells in Allergic Skin Disease
a crucial role in inducing immunity and tolerance. In our recent work, we have shown a successful treatment using CD86 siRNA targeting cutaneous DCs. A costimulatory molecule, CD86, is induced on DCs in situ after antigen uptake, and CD86
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