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- 详细信息
- 技术资料
- 亚型:
IgG
- 形态:
液体
- 保存条件:
-20℃
- 克隆性:
多克隆
- 标记物:
无
- 适应物种:
HM
- 保质期:
一年
- 抗原来源:
兔
- 供应商:
万类生物
- 宿主:
兔
- 应用范围:
WB,IHC,IF
- 浓度:
>1 mg/ml
- 靶点:
IL8
- 抗体英文名:
IL8 antibody
- 抗体名:
IL8 抗体
- 规格:
50μl(>50μg)
产品概述
Interleukin-8, or IL-8, the prototypic member of the C-X-C, or a, family of chemokines, is a chemoattractant cytokine involved in the chemotaxis and activation of neutrophils. IL-8 is produced by a number of cell types including monocytes, T cells, neutrophils, fibroblasts, endothelial cells, and others. In addition to its effects on neutrophils, IL-8 promotes angiogenesis, inhibits endothelial cell apoptosis, and promotes the proliferation of melanoma cells in an autocrine fashion. IL-8 monomers and dimers exhibit a dynamic equilibrium both free in solution and in cell surface-bound forms and thus regulate chemotaxis and receptor signaling. Research has shown that IL-8 dimerization functions as a negative regulator for IL-8 receptor function.
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