IDDM;IDDM1;IDDM2;ILPR;ins;INS_HUMAN;Insulin A chain;Insulin B chain;IRDN;MODY10;Preproinsulin;Proinsulin;Proinsulin precursor;
背景资料
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
保存
Store at -20°C. Avoid freeze / thaw cycles.
交叉反应
Human;Mouse;Rat
应用
IHC
规格
50ul 100ul
单位
支
备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示:
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图
Immunohistochemistry of paraffin-embedded Human colorectal cancer with INS antibody diluted at 1:100