Supelco货号59683-U现货Supel™ BioSP

Supelco货号59683-U现货Supel™ BioSPME 96-Pin Device上海睿安生物13611631389

 

一般描述

The Supel^™ BioSPME 96-Pin Device combines BioSPME technology with high throughput free fraction determination for plasma protein binding studies and other free analyte analyses commonly performed by pharma and clinical laboratories. This fast, micro-sample prep device comprises a 96-pin universal format that fits into the wells of standard 96-well plates. The pins are coated with C18 particles and a patented binder that allows for small analytes of interest to bind, while larger macromolecules cannot. This extraction technique is shown to be more than three times faster than rapid equilibrium dialysis methods with improved data quality. Supel^™ BioSPME 96-Pin Device workflow can be performed on automation robots via handling with standard gripper paddles, or alternatively can be achieved using a manual technique.

分析说明

small molecules having molecular weights up to 1 kDa and logP range from 1-5


Supel™ BioSPME 96针装置将BioSPME技术与高通量游离组分测定相结合，用于血浆蛋白结合研究和制药和临床实验室通常进行的其他游离分析物分析。这种快速、微量样品制备装置包括96针通用格式，适合标准96孔板的孔。这些针涂有C18颗粒和一种专利粘合剂，允许小的感兴趣的分析物结合，而大的大分子不能结合。这种提取技术被证明比快速平衡透析方法快三倍以上，数据质量得到改善。Supel™ BioSPME 96针装置的工作流程可以通过使用标准夹持器叶片在自动化机器人上执行，或者可以使用手动技术实现。