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Granzyme B Rabbit pAb

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  • ¥600 - 1800
  • 戴格
  • 2025年07月11日
  • WB,IHC,IP
  • Rabbit
  • Human, Mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

    • 适应物种

      Human, Mouse

    • 保质期

      12个月

    • 库存

      现货

    • 宿主

      Rabbit

    • 应用范围

      WB,IHC,IP

    • 靶点

      Granzyme B

    • 规格

      20μL/50μL/100μL

    规格:20μL产品价格:¥600.0
    规格:50μL产品价格:¥1000.0
    规格:100μL产品价格:¥1800.0
    This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]

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    图标文献和实验
    相关实验
    • Granzyme A、B介导的凋亡信号通路

      and virus-infected cells is the release of perforin and granzyme proteins. Perforin proteins form pores in the membranes of the attacked cell, allowing the entry of Granzyme A and Granzyme B. Granzyme B induces caspase activation and cleavage of factors

    • Immunodetection of Granzyme B Tissue Distribution and Cellular Localisation

      Investigation of Granzyme B (GrB) function and pathophysiology in both human settings and rodent models increasingly involve the use of indirect immunofluorescence imaging and fluorescence-activated cell sorting, which requires reliable GrB

    • Detection of Human and Mouse Granzyme B Activity in Cell Extracts

      The serine protease granzyme B (GrB) is a key effector molecule in cell-mediated immunity, released by cytotoxic lymphocytes (CLs) to induce cell death in neoplastic or virus-infected cells. The ability to detect and measure GrB activity

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