钙黄绿素-AM，148504-34-1

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试剂描述：

产品名称：钙黄绿素-AM

产品别名：钙荧光素-AM；钙黄绿素乙酰甲酯

CAS号：148504-34-1

英文别名：钙黄绿素-AM

分子量：994.86

分子式：C₄₆H₄₆N₂O₂₃

纯度：≥95%

外观：见爱必信官网

保存方法：Store at -20° C,2 years.

描述：

Calcein-AM is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein , which is an extremely fluorescent and negatively charged molecule. The probe can be used to stain living cells and has been observed to fluoresce bright green in cytoplasmic Schwann cells. Calcein-AM has been reported to be a neutral substrate for Mdr (P-glycoprotein (Pgp) and multidrug resistance protein (MRP)) and has been used in flow cytometry studies to analyze the function of P-gp and MRP. Studies suggest that Calcein-AM can be used to detect MDR mediated resistance and to be transported by PGP from the plasma membrane. Mitochondrial permeability research has utilized Calcein as a cytosolic fluorophore. Has been used as a cytosolic fluorophore in mitochondrial permeability studies to image pore transition.

应用：A non-fluorescent, membrane permeable probe that can be hydrolyzed to a fluorescent molecule

分子结构图：

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