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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
-
- 抗体英文名:
,ARB1; ARR1; ARRB1; ARRB1_HUMAN; Arrestin 2; Arrestin beta 1; Arrestin beta-1; Beta-arrestin-1.
- 靶点:
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- 浓度:
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- 应用范围:
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- 宿主:
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- 适应物种:
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- 保质期:
-
- 抗原来源:
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- 目录编号:
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- 级别:
-
- 库存:
99
- 供应商:
爱必信(上海)生物科技有限公司
- 标记物:
-
- 克隆性:
-
- 保存条件:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
- 形态:
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- 亚型:
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- 免疫原:
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- 规格:
100ul
| 概述 | |
| 别名 | ARB1; ARR1; ARRB1; ARRB1_HUMAN; Arrestin 2; Arrestin beta 1; Arrestin beta-1; Beta-arrestin-1. |
| 宿主 | Mouse |
| 反应种属 | Human |
| 应用 | WB: 1/500-1/1000 |
| 分子量 | Detects a band of approximately 51 kD(Predicted molecular weight: 47 kD) Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 免疫原 | Recombinant human β-Arrestin 1 protein. |
| 性能 | |
| 形式 | Monoclonal Antibody |
| 纯化方法 | Affinity Purified |
| 克隆号 | 6A1 |
| 同种型 | IgG2b |
| 储存/保存方法 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 存储溶液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| 修饰 | Unmodified |
| 靶标 | |
| 背景说明 | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011] |
| UniProt | P49407 |
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