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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名:
,EFCAB4B, RAB46
- 库存:
99
- 供应商:
爱必信(上海)生物科技有限公司
- 保存条件:
储存温度:-20℃,避免反复冻融
- 规格:
100ul
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抗体描述: 产品名称:Mouse anti-CRACR2A Monoclonal Antibody 产品别名:CRACR2A抗体 宿主:Mouse 反应种属:Human 克隆性:Monoclonal Antibody 保存方法:储存温度:-20℃,避免反复冻融 产品描述:Ca2+结合蛋白,通过调节CRAC通道激活,在T细胞的钙池操纵Ca2+通道的打开(SOCE)中发挥关键作用。作为细胞质钙传感器,在低Ca2+浓度时,促进ORAI1和STIM1在质膜和内质网交界处聚集,从而调控CRAC通道的激活,包括ORAI1和STIM1的易位和聚集。当CRAC通道打开导致细胞质Ca2+增加时,从ORAI1和STIM1分离,从而使ORAI1-STIM1复合物不稳定。 用途范围:WB:1:500-1:1000
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文献和实验Rapid Isotyping of Mouse Monoclonal Antibodies
, isotyping is useful to control lot to lot consistency, detect contamination by another antibody, and identify hybridoma switch variants (see Notes 2 –8 for further comment on applications). Table 1 Isotype-Dependent Properties of Monoclonal
Isolation of Human Monoclonal Antibodies Using Guided Selection with Mouse Monoclonal Antibodies
Repertoires of antibody (Ab) V genes derived from nonimmunized human donors (1 ) or made synthetically (2 3 ) have been cloned for display on filamentous bacteriophage as either scFvs or Fabs fused to the minor phage coat protein (pIII
Isotype-specific immunostaining with mouse primary antibodies on mouse tissue
) Briefly, substitute your anti H+L pan-reactive secondary antibody with an anti-isotype heavy chain specific secondary. Be aware of possible odd crossreactivties (e.g. many goat anti mouse IgG 1 heavy chain do stain rat IgG 2a
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