- ￥4697
- Merck-Calbiochem
- 218785-3000U
- 2025年07月09日
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
Merck
- 英文名：
Caspase-10 Human Recomb.
- 库存：
大量
- 规格：
3000U
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文献和实验Cleavage by granzyme B, caspase-6, caspase-8 and caspase-10 generates the two active subunits. Additional processing of the propeptides is likely due to the autocatalytic activity of the activated protease. Active heterodimers between the small subunit
Biochemical Analysis of the Native TRAIL Death-Inducing Signaling Complex
years. For the CD95 and the TRAIL-R1/R2 DISCs, it is now clear that the adaptor protein Fas-associated DD protein (FADD) forms part of these complexes and is necessary for recruitment of the pro-apoptotic signaling molecules caspase-8 and caspase-10
to activate the caspase proteolytic cascade. Caspase-8 and caspase-10 are first activated, to then cleave and activate downstream caspases, and a variety of cellular substrates that lead to cell death. Caspases cleave nuclear lamins, causing the nucleus
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