- ￥1280 - 1980
- YLKBIO
- YLK-KT2008D
- 国产
- 2025年07月14日
- WB、ELISA
- Human, Dog, Sheep, Monkey
- /
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
优利科（上海）生命科学有限公司
- 库存：
88
- 靶点：
详询
- 级别：
科研
- 目录编号：
/
- 克隆性：
多克隆
- 抗原来源：
详见说明书
- 保质期：
1年
- 抗体英文名：
Anti-Inhibin Alpha
- 抗体名：
Inhibin Alpha抗体
- 标记物：
详询
- 宿主：
Human, Dog, Sheep, Monkey
- 适应物种：
/
- 免疫原：
KLH conjugated synthetic peptide derived from human Inhibin Alpha
- 亚型：
IgG
- 形态：
Lyophilized or Liquid
- 应用范围：
WB、ELISA
- 保存条件：
-20℃
- 浓度：
1mg/ml
- 规格：
详询
| 英文名称 Anti-Inhibin Alpha |
| 中文名称 抑制素A/Inhibin α抗体 |
| 别 名 A inhibin subunit precursor; IHA; INHA; Inhibin alpha chain; Inhibin alpha chain precursor; Inhibin alpha subunit; INHA_HUMAN. |
| 浓 度 1mg/1ml |
| 规 格 0.2ml/200μg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Human, Dog, Sheep, Monkey |
| 产品类型 一抗 |
研究领域 肿瘤 神经生物学 信号转导 生长因子和激素  |
| 蛋白分子量 predicted molecular weight: 15kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from human Inhibin Alpha |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
| （石蜡切片需做抗原修复） |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
| 保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. |
| Function : Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. |
| Subunit : Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B. |
Subcellular Location : Secreted. |
| Tissue Specificity : Originally found in ovary (granulosa cells) and testis (Sertoli cells), but widely distributed in many tissues including brain and placenta. In adrenal cortex expression is limited to the zona reticularis and the innermost zona fasciculate in the normal gland, extending centripetally into the zona fasciculata in hyperplasia. Also found in adrenocortical tumors. Also expressed in prostate epithelium of benign prostatic hyperplasia, in regions of basal cell hyperplasia and in nonmalignant regions of high grade prostate cancer. Only circulating inhibin B is found in male, whereas circulating inhibins A and B are found in female. |
| Post-translational modifications : Proteolytic processing yields a number of bioactive forms. The 20/23 kDa forms consist solely of the mature alpha chain, the 26/29 kDa forms consist of the most N-terminal propeptide linked through a disulfide bond to the mature alpha chain, the 50/53 kDa forms encompass the entire proprotein. Each type can be furthermore either mono- or diglycosylated, causing the mass difference. |
| Similarity : Belongs to the TGF-beta family. |
| Database links : UniProtKB/Swiss-Prot: P05111.1 human |
| Inhibin-α是一种二聚体蛋白质激素，由卵巢粒层细胞产生，能抑制垂体促性腺激素的产生和分泌。该抗体用于研究生殖轴基质性肿瘤 |
| β-Amyloid fragment（1-42）Rat β淀粉样肽（1-42）大鼠 |
| β-Amyloid（1-40) β淀粉样肽1-40（多肽蛋白） |
| β-Amyloid fragment（1-42） β淀粉样肽（1-42）（抗原） |
| β-Amyloid 25-35 Aβ 25-35 β-淀粉样肽25-35 |
| β-Amyloid 1-42 CT β淀粉样肽 1-42 (C端多肽) |
| Amylin 糖尿病相关肽（胰岛淀粉样肽） |
| APP695-770/APP17肽 （Amyloid protein precursor） 淀粉样肽前体蛋白（17肽抗原） |
| Neuroprotective peptide/Gly-HN(Nuclear-encoded Humanin [HN(N)] Gly14) 神经保护肽 |
| Amylin(1-37) 糖尿病相关肽（胰岛淀粉样肽） |
| CCP peptide (cyclic citrullinated peptide,CCP) 瓜氨酸环肽 |
| CCP peptide (cyclic citrullinated peptide,CCP) 瓜氨酸环肽 |
| GLP-1（Glucagon-like peptide-1）(7-36) 胰高血糖素样肽-1（多肽） |
| GRGDS peptide 抗黏附多肽GRGDS |
| PACAP(1-38 Peptide) 腺苷酸环化酶激活肽 1-38（全蛋白） |
| MBP Antigen(Myelin Basic Protein, MBP) 髓鞘碱性蛋白(多肽抗原) |
| Leupeptin 亮抑酶肽 |
| GRP（ Gastrin Releasing Peptide ） 促胃泌素释放肽（抗原） |
| YTA（标准） 牛血清白蛋白（标准 |
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抑制素A/Inhibin α抗体
￥1280 - 1980
