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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20°C/-80°C
- 保质期:
12个月
- 英文名:
Recombinant Human Tumor necrosis factor ligand superfamily member 8(TNFSF8)
- 库存:
4
- 供应商:
上海禾午生物科技有限公司
- 规格:
20ug/100ug/1mg
产品详情
纯度:Greater than 94% as determined by SDS-PAGE.
内毒素:Less than 1.0 EU/ug as determined by LAL method.
生物活性:Measured by its binding ability in a functional ELISA. Immobilized CD30 at 5 μg/ml can bind human CD30L, the EC50 is 4.169-6.360 ng/ml.
基因名:TNFSF8
Uniprot No.:P32971
别名:TNFSF8; CD30L; CD30LG; Tumor necrosis factor ligand superfamily member 8; CD30 ligand; CD30-L; CD antigen CD153
种属:Homo sapiens (Human)
蛋白长度:Partial
来源:Mammalian cell
分子量:45.8
表达区域:63-234aa
蛋白标签:N-terminal hFc-tagged
产品提供形式:Lyophilized powder
产品描述:在哺乳动物细胞中表达了人的TNFSF8氨基酸(Gln63-Asp234)。氨基端包含人类IgG1 fc标签。该产品为部分长度重组TNFSF8蛋白。SDS-PAGE检测蛋白纯度大于94%。这种TNFSF8蛋白迁移到凝胶上分子量约为55 kDa的地方。LAL法测定TNFSF8蛋白内毒素含量小于1.0 EU/ug。通过功能性ELISA,该TNFSF8蛋白被证实具有生物活性。受体TNFRSF8可与TNFSF8蛋白结合,EC50约为4.169 ~ 6.360 ng/ml。现在有现货。
TNFSF8也被称为CD153或CD30L,在活化的CD4+、CD8+ T细胞、B细胞和巨噬细胞上表达。它介导B细胞的生长和分化。Nancy D Marín和Luis F García发现TNFSF8-TNFRSF8在T细胞依赖的抗分枝杆菌免疫反应中发挥关键作用。
更多活性蛋白请浏览上海禾午生物科技有限公司
上海禾午生物科技有限公司 提供重组蛋白生产服务 His、GST、MBP等多种表达方式同时进行,确保获得蛋白
蛋白表达与纯化服务 纯化的蛋白经过ELISA,Western-blot,或者其它生物活性验证 标签切除 测序报告
上海禾午生物科技有限公司是一家生物高新技术企业,产品覆盖分子生物学、细胞生物学、生物学试剂、标准物质,等领域。以研发、销售为核心致力于生命科学产品。已与全国各大科研院校、医院、企业以及国外一些科研机构有良好的合作关系。
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文献和实验Induction of Tumor Cell Apoptosis by TRAIL Gene Therapy
Members of the tumor necrosis factor (TNF) superfamily influence a variety of immunological functions, including cellular activation, proliferation, and death, upon interaction with a corresponding superfamily of receptors
Among cytokine families, the tumor necrosis factor (TNF) superfamily stands out as the one that contains several members with cytotoxic activity (1 –3 ). The best characterized is the prototypic member TNF-α, which is cytotoxic to a range
Biochemical Analysis of the Native TRAIL Death-Inducing Signaling Complex
The extrinsic apoptosis pathway is activated when certain members of the tumor necrosis factor (TNF) receptor superfamily (TNFRSF) are oligomerized by their cognate ligands that are members of the TNF superfamily (TNFSF). The apoptosis
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