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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20°C/-80°C
- 保质期:
12个月
- 英文名:
Recombinant Human Growth hormone receptor(GHR)
- 库存:
4
- 供应商:
上海禾午生物科技有限公司
- 规格:
20ug/100ug/1mg
产品详情
纯度:Greater than 93% as determined by SDS-PAGE.
内毒素:Less than 1.0 EU/ug as determined by LAL method.
生物活性:①Measured by its binding ability in a functional ELISA. Immobilized GH1 at 1 μg/ml can bind human GHR, the EC50 of human GHR protein is 24.96-33.39 ng/ml.②Human GH1 protein his/myc tag captured on COOH chip can bind Human GHR protein Fc tag with an affinity constant of 6.1 nM as detected by LSPR Assay.
基因名:GHR
Uniprot No.:P10912
别名:Somatotropin receptor (Serum-binding protein)
种属:Homo sapiens (Human)
蛋白长度:Partial
来源:Mammalian cell
分子量:58.8 kDa
表达区域:27-264aa
蛋白标签:C-terminal hFc-tagged
产品提供形式:Lyophilized powder
产品描述:重组人粘蛋白16 (MUC16)是通过在哺乳动物细胞中表达人GHR蛋白的氨基酸Ala27-Tyr264对应的DNA片段而产生的。它的c端带有人类IgG1 Fc标签。该蛋白纯度高(>93%,SDS-PAGE),内毒素含量低(< 1.0 EU/ug蛋白,LAL法)。由于糖基化作用,GHR蛋白的分子量约为70 kDa。通过功能ELISA和LSPR实验验证其生物活性。现在有现货。
GHR属于I类细胞因子受体家族,广泛表达于GH靶细胞。GHR与GH结合激活多种信号级联,导致生长促进、细胞分裂和再生。GH-GHR相互作用还影响碳水化合物、脂质和蛋白质的代谢,塑造身体组成,影响心血管状况,以及其他生理效应。
更多活性蛋白请浏览上海禾午生物科技有限公司
上海禾午生物科技有限公司 提供重组蛋白生产服务 His、GST、MBP等多种表达方式同时进行,确保获得蛋白
蛋白表达与纯化服务 纯化的蛋白经过ELISA,Western-blot,或者其它生物活性验证 标签切除 测序报告
上海禾午生物科技有限公司是一家生物高新技术企业,产品覆盖分子生物学、细胞生物学、生物学试剂、标准物质,等领域。以研发、销售为核心致力于生命科学产品。已与全国各大科研院校、医院、企业以及国外一些科研机构有良好的合作关系。
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