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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20°C/-80°C
- 保质期:
12个月
- 英文名:
Recombinant Human N-terminal Xaa-Pro-Lys N-methyltransferase 1(NTMT1)
- 库存:
4
- 供应商:
上海禾午生物科技有限公司
- 规格:
20ug/100ug/1mg
产品详情
纯度:Greater than 85% as determined by SDS-PAGE.
生物活性:Measured by its binding ability in a functional ELISA. Immobilized CCL5 at 2 μg/ml can bind human NTMT1, the EC50 of human NTMT1 protein is 3.029-5.404 μg/ml.
基因名:NTMT1
Uniprot No.:Q9BV86
别名:AD 003; Alpha N-terminal protein methyltransferase 1A; C9orf32; Chromosome 9 open reading frame 32; Methyltransferase like 11A; Methyltransferase-like protein 11A; Mettl11a; N-terminal RCC1 methyltransferase; NRMT; NTM1A; NTM1A_HUMAN; NTMT1; X-Pro-Lys N-terminal protein methyltransferase 1A
种属:Homo sapiens (Human)
蛋白长度:Full Length of Mature Protein
来源:E.coli
分子量:52.3 kDa
表达区域:2-223aa
蛋白标签:N-terminal GST-tagged
产品提供形式:Liquid or Lyophilized powder
功能:分布型α - n甲基转移酶,当启动子Met被切割时,使含有n端基序[Ala/Gly/Pro/Ser]-Pro-Lys的靶蛋白n端甲基化。特异性催化[Ala/Gly/Ser]-Pro- lys基序中Ala、Gly或Ser残基暴露的α -氨基的一甲基化、二甲基化或三甲基化以及Pro-Pro- lys基序中Pro的一甲基化或二甲基化。一些底物可能被ntmt2介导的单甲基化启动。催化CENPA中n端Gly的三甲基化(去除Met-1后)。负责KLHL31、MYL2、MYL3、RB1、RCC1、RPL23A、SET的n端甲基化。在有丝分裂过程中,正常双极纺锤体形成和染色体分离所必需的RCC1的作用。
更多活性蛋白请浏览上海禾午生物科技有限公司
上海禾午生物科技有限公司 提供重组蛋白生产服务 His、GST、MBP等多种表达方式同时进行,确保获得蛋白
蛋白表达与纯化服务 纯化的蛋白经过ELISA,Western-blot,或者其它生物活性验证 标签切除 测序报告
上海禾午生物科技有限公司是一家生物高新技术企业,产品覆盖分子生物学、细胞生物学、生物学试剂、标准物质,等领域。以研发、销售为核心致力于生命科学产品。已与全国各大科研院校、医院、企业以及国外一些科研机构有良好的合作关系。
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文献和实验The Use of TAGZyme for the Efficient Removal of N-Terminal His-Tags
is unwanted or may represent a disadvantage for the projected use of the protein, like in clinical, functional or structural studies. For N-terminal tags, the TAGZyme system represents an ideal approach for fast and accurate tag removal. TAGZyme is based
Expression of Recombinant Proteins with Uniform N-Termini
Heterologously expressed proteins in Escherichia coli may undergo unwanted N-terminal processing by methionine and proline aminopeptidases. To overcome this problem, we present a system where the gene of interest is cloned as a fusion
Benzydamine N-Oxygenation as a Measure of Flavin-Containing Monooxygenase Activity
reverse-phase high-performance liquid chromatography (HPLC) assay with fluorescence detection. Studies with recombinant FMO enzymes demonstrate that FMO1 and FMO3 are the primary catalysts of benzydamine N -oxygenation, with minimal contributions
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