Anti-PNPLA8 Polyclonal Antibod

Anti-PNPLA8 Polyclonal Antibody


产品简介

靶标	PNPLA8
别名	Calcium-independent phospholipase A2-gamma; Intracellular membrane associated calcium independent phospholipase A2 gamma; Intracellular membrane-associated calcium-independent phospholipase A2 gamma; IPLA2 2; iPLA2 gamma
宿主	Rabbit
稀释比例	IHC 1:50-200.
Gene ID	50640
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	Q9NP80
蛋白分子量	77/82/88kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Cytoplasm
免疫原	A synthetic peptide of human PNPLA8
亚型	IgG
纯化方法	Affinity purification
背景资料	Calcium-independent phospholipase A2, which promotes cellular membrane hydrolysis and prostaglandin production (PubMed:10744668, PubMed:15695510). Catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, phosphytidylserine and to a lower extent phosphatidylcholine (PubMed:10744668). Cleaves membrane phospholipids (PubMed:15695510). Participates in the generation of lipid second messengers through the mobilization of arachidonic acid in response to cellular stimuli. Synthesizes 2-arachidonoyl lysophosphatidylcholine, a key branch point metabolite in eicosanoid signaling (PubMed:15908428). Participates in the lipid plasticity of myocardium, plays a role in the generation of signaling metabolites and has a prominent effect on the modulaton of energy storage and utilization (PubMed:17213206). Essential for maintaining efficient bioenergetic mitochondrial function through tailoring mitochondrial membrane lipid metabolism and composition (By similarity).
Public Immunogen Range	200-250/782aa
克隆类型	Polyclonal Antibody
交叉反应	Human
应用	IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Immunohistochemistry of paraffin-embedded Human colorectal cancer with PNPLA8 antibody diluted at 1:100.