SKI-I,306301-68-8

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SKI-I

CAS No. : 306301-68-8

MCE 国际站：SKI-I

产品活性：SKI-I 是一种有效和选择性的人鞘氨醇激酶 (SK) 抑制剂，抑制 ST-hSK 的 IC₅₀ 值为 1.2 μM。SKI-I 还抑制 hERK2 (IC₅₀=11 μM)。SKI-I 在肿瘤细胞系中诱导细胞凋亡。

研究领域：Immunology/Inflammation  |  Apoptosis

作用靶点：SphK  |  Apoptosis

In Vitro: SKI-I (Compound I; 5 μg/mL) inhibits SK activity by 99%.
SKI-I (10 μM; 24 h) induces the apoptosis of T24 cells.

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