- ￥600 - 2200
- Proteintech
- 65140-1-Ig
- 2025年10月13日
- FC
- Rat
- mouse
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- 文献和实验
- 技术资料
- 免疫原：
None
- 亚型：
IgG2b, kappa
- 保存条件：
Store at 2-8°C. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
mouse
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Rat
- 应用范围：
FC
- 靶点：
Ly-6G/Ly-6C (Gr-1)
- 抗体英文名：
Anti-Mouse Ly-6G/Ly-6C (Gr-1) (RB6-8C5)
- 抗体名：
Anti-Mouse Ly-6G/Ly-6C (Gr-1) (RB6-8C5)
- 规格：
100ug/500ug
| 规格： | 100ug | 产品价格： | ￥600.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥2200.0 |
经过测试的应用
| Positive FC detected in | mouse bone marrow cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.5 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
65140-1-Ig targets Ly-6G/Ly-6C (Gr-1) in WB, FC applications and shows reactivity with mouse samples.
| 经测试应用 | FC |
| 文献引用应用 | WB, FC |
| 经测试反应性 | mouse |
| 文献引用反应性 | mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rat / IgG2b, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | lymphocyte antigen 6 complex, locus G |
| 别名 | Gr-1, Ly6g, Ly 6G, Ly-6G, Ly-6G.1 |
| GenBank蛋白编号 | X70920 |
| 基因名称 | Ly-6G |
| Gene ID (NCBI) | 546644 |
| RRID | AB_2881475 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | P35461 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
Ly-6G (lymphocyte antigen 6 complex, locus G), also known as Gr-1, is a 21-25 kDa, glycosylphosphatidylinositol-anchored protein expressed on myeloid lineage cells in mouse bone marrow (PMID: 8360469). The expression of Ly-6G increases on neutrophils as they differentiate from immature cells in the bone marrow to mature cells in the blood and spleen (PMID: 8890901). Antibodies targeting Ly6G (RB6-8C5 or 1A8) are commonly used in studies aimed at identifying the role of neutrophils (PMID: 23543767). The RB6-8C5 mAb has been reported to cross-react with Ly-6C on cells expressing Ly-6C (PMID: 8360469).
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文献和实验| Species | Application | Title |
|---|---|---|
| mouse | FC | J Leukoc Biol The effect of an isoquinoline alkaloid on treatment of periodontitis by regulating the neutrophils chemotaxis.Authors - Yitong Liu |
| mouse | FC | J Oncol Blocking TGF-β Expression Attenuates Tumor Growth in Lung Cancers, Potentially Mediated by Skewing Development of Neutrophils.Authors - Yifei Fang |
Life Sci Icariside II alleviates lipopolysaccharide-induced acute lung injury by inhibiting lung epithelial inflammatory and immune responses mediated by neutrophil extracellular trapsAuthors - Xiuchun Li | ||
| mouse | Eur J Pharmacol Involvement of necroptotic cell death in macrophages in progression of bleomycin and LPS-induced acute exacerbation of idiopathic pulmonary fibrosisAuthors - Atsushi Koike | |
Sci Rep Social defeat stress induces liver injury by modulating endoplasmic reticulum stress in C57BL/6J miceAuthors - XiaoLei Gao | ||
| mouse | Biomaterials Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individualsAuthors - Shuai-Dong Chen |
-mouse CD3e (CD3 e chain)； 2) Biotin-anti-mouse CD11b； 3) Biotin-anti-mouse CD45R/B220； 4) Biotin-anti-mouse Ly-6G and Ly-6C (Gr-1)； 5) Biotin-anti-mouse TER-119/Erythroid Cells (Ly-76) 磁分离细胞的重要指标是：
Elabscience|肺泡巨噬细胞研究必看：LPS诱导急性肺炎模型制备与检测全攻略
抗体[X54-5/7.1] E-AB-F09792C FITC 标记小鼠IgG1，κ同型对照抗体[MOPC-21] E-AB-F1120D PE 标记抗小鼠Ly-6G/Ly-6C（Gr-1）抗体[RB6-8C5] E-AB-F0991H PE/Cyanine7 标记抗小鼠CD11c抗体[N418] AN00629J PerCP/Cyanine5.5 标记抗小鼠Siglec-F/CD170抗体[S17007L] E-AB-F0997A 纯化抗小鼠CD16/32抗体[2.4G
D Granulocytic : Gr-1 (Ly-6G) IgG2b, 01211A D8 IgG2b, 09821D Eryth: Ter-119 IgG2b, 09081A Sca-1 PE-IgG2a (E31-161.7) 01835B PE-IgG2a Isotype control, 11025
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