- 询价
- Cell Signaling Technology
- 4102
- USA
- 2025年09月03日
- W
- Rabbit
- M,H
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- 详细信息
- 询价记录
- 技术资料
- 抗体英文名：
ROR1 Antibody
- 抗原：
synthetic peptide corresponding to the residues at the amino-terminal sequence of human ROR1
- 应用范围：
W
- 宿主：
Rabbit
- 保质期：
详见说明书
- 供应商：
CST
- 级别：
详见MSDS文件
- 库存：
大量
- 适应物种：
M,H
- 是否单克隆：
2
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting
Reactivity Key: H=Human M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W | M (H) | Transfected Only | 135 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | ROR1 Antibody detects transfected levels of ROR1 proteins. It does not cross-react with ROR2. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the residues at the amino-terminal sequence of human ROR1. The antibodies are purified by protein A and peptide affinity chromatography. Western Blotting
Western blot analysis of extracts from HEK293 cells, untransfected or transfected with HA-tagged mROR1, using ROR1 Antibody (upper) or HA-tag Antibody #2362 (lower). |
| Background | ROR1 and ROR2 are orphan receptor tyrosine kinases that are most closely related to MuSK and the Trk family of neurotrophin receptors. They are characterized by the presence of extracellular frizzled-like cysteine-rich domains and membrane-proximal kringle domains, both of which are assumed to mediate protein-protein interactions (1-3). The ROR family RTKs are evolutionarily conserved among Caenorhabditis elegans, Drosophila, mice, and humans (1,4). Although the functions of ROR kinases are unknown, similarities between ROR and MuSK and Trk kinases have led to speculation that ROR kinases regulate synaptic development. CAM-1, a C. elegans ortholog of the ROR family RTKs, plays several important roles in regulating cellular migration, polarity of asymmetric cell divisions, and axonal outgrowth of neurons during nematode development (4). mROR1 and mROR2 may play differential roles during the development of the nervous system (5). |
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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