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Cytochrome c An
tibodyCytochrome c Antibody
synthetic peptide corresponding to amino acids 67-78 of human cytochrome c
W, IHC-P
Rabbit
详见MSDS文件
CST
详见说明书
大量
H,M,R,Mk,Dm,B
2
-20°c
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting IHC-P=Immunohistochemistry (Paraffin)
Reactivity Key: H=Human M=Mouse R=Rat Mk=Monkey Dm=D. melanogaster B=Bovine
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W IHC-P | H M R Mk Dm (B) | Endogenous | 14 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | Cytochrome c Antibody detects endogenous levels of cytochrome c protein. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to amino acids 67-78 of human cytochrome c. Antibodies are purified by protein A and peptide affinity chromatography. Western Blotting
Western analysis of cell extracts from human (HeLa and Jurkat), monkey (COS), mouse (L929), rat (C6) and purified bovine cytochrome c, using Cytochrome c Antibody. IHC-P (paraffin)
Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using Cytochrome c Antibody. IHC-P (paraffin)
Immunohistochemical analysis of paraffin-embedded human prostate carcinoma, using Cytochrome c Antibody. |
| Background | Cytochrome c is a well conserved electron-transport protein and is part of the respiratory chain localized to mitochondrial intermembrane space (1). Upon apoptotic stimulation, cytochrome c released from mitochondria associates with procaspase-9 (47 kDa)/Apaf 1. This complex processes caspase-9 from inactive proenzyme to its active form (2). This event further triggers caspase-3 activation and eventually leads to apoptosis (3). |
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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