- 询价
- Cell Signaling Technology
- 9494
- USA
- 2026年05月28日
- W
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- 文献和实验
- 技术资料
- 抗体英文名：
Caspase-7 (C7) Mouse mAb (Human Specific)
- 抗原：
recombinant human caspase-7 protein
- 应用范围：
W
- 供应商：
CST
- 保质期：
详见说明书
- 库存：
大量
- 适应物种：
H
- 级别：
详见MSDS文件
- 是否单克隆：
1
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting
Reactivity Key: H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Isotype |
|---|---|---|---|---|
| W | H | Endogenous | 20, 30, 35 | Mouse IgG1 |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | Caspase-7 (C7) Mouse mAb (Human Specific) detects endogenous levels of caspase-7 proform as well as the 30 and 20 kDa cleaved fragments. This antibody does not cross-react with other caspases. |
| Source / Purification | Monoclonal antibody is produced by immunizing animals with a recombinant human caspase-7 protein. Western Blotting
Western blot analysis of extract from Jurkat cells, untreated or etoposide-treated, using Caspase-7 (C7) Mouse mAb (Human Specific). |
| Background | Caspase-7 (CMH-1, Mch3, ICE-LAP3) has been identified as a major contributor to the execution of apoptosis (1-4). Caspase-7, like caspase-3, is an effector caspase that is responsible for cleaving downstream substrates such as (ADP-ribose) polymerase and PARP (1,3). During apoptosis, caspase-7 is activated through proteolytic processsing by upstream caspases at Asp23, Asp198, and Asp206 to produce the mature subunits (1,3). Similar to caspases-2 and -3, caspase-7 preferentially cleaves substrates following the recognition sequence DEVD (5). |
| Application References |
Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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Hybrid Resistance by Mouse NK Cells In Vitro
of monoclonal antibodies (MAbs) or F(ab′)2 reagents to block those signals. There is already good evidence for negative signals between Ly49 NK cell receptors and their specific class I antigens, e.g., Ly49A and H2-Dd (2 ). Thus, the inability of H2b Ly49
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