All Biointron antibodys guaranteed shelf-life of one year from the date of customer receipt when stored as recommended. It is not uncommon for a floccule or precipitate to appear during storage.
抗原来源:
NA
目录编号:
B129601
级别:
Research Use only
库存:
99
供应商:
百英生物(Biointron)
标记物:
Unconjugated
克隆性:
单克隆
保存条件:
This antibody can be stored at 2°C to 8°C for 2 weeks under sterile conditions; -20°C for 3 months under sterile conditions; -70°C for 36 months under sterile conditions. Avoid repeated freeze-thaw
形态:
PBS, pH 7.0 Contains no stabilizers or preservatives
亚型:
Mouse IgG1-Kappa
免疫原:
Recombinant.The details of the immunogen for this antibody are not available.
规格:
1mg
The critical role of CTLA-4 in immune down-regulation has been demonstrated in CTLA-4 deficient mice, which succumb at 3-5 weeks of age due to the development of a lymphoproliferative disease. CTLA-4 is among a group of inhibitory receptors being explored as cancer treatment targets through immune checkpoint blockade. The UC10-4F10-11 antibody has been shown to promote T cell co-stimulation by blocking CTLA-4 binding to the B7 co-receptors, allowing for CD28 binding.
蛋白纯度:> 95% as determined by SDS-PAGE 蛋白内毒素:<1EU/mg, Determined by LAL gel clotting assay 百英生物(Biointron)成立于2012年,是一家专注于抗体早期发现CRO服务的行业龙头企业。目前在江苏泰州设有研发和生产基地,在上海张江和广州科学城设有研发中心,在美国和荷兰设有商务中心等分支机构。公司建有10000多平米符合GMP规范的标准厂房,通过了ISO9001:2015体系认证和两化融合体系贯标,是国家高新技术企业、国家规模以上工业企业、国家科技型中小企业、江苏省服务外包协会理事单位,也是泰州市抗体发现工程研究中心和公共服务平台。 百英生物拥有高通量抗体表达平台,“抗体表达,一周交付”,从基因合成到纯化抗体交付,只需要一周时间,为全球近千家企业交付了数万个抗体分子。百英生物拥有单细胞抗体开发平台,利用微流控分选与鉴定技术,快速筛选候选分子。拥有噬菌体库抗体开发平台,全人源抗体库、各种属免疫库等丰富的建库与淘选经验。拥有羊驼及鲨鱼纳米抗体开发平台,为双抗研发、细胞治疗提供支持。拥有ECACC的CHO-K1细胞株全球授权权利,可提供高表达稳定细胞株的开发,PD小试工艺优化以及宿主细胞授权。拥有抗体人源化、亲和力成熟等抗体工程改造平台,以及全面的药效评价平台。还拥有大量现货与活性验证的体内实验用药物通用抗体等产品。致力于打造成为真正只做服务的抗体药物研发专家。