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cyp26a1多克隆抗体
- 参考价格： ¥1100.0 - 2310.0
- 品 牌： abgent
- 货 号： AP2754d
- 适应物种： 人,小鼠
- 应用范围： 免疫印迹,免疫组化,流式细胞技术
- 克 隆 性： 多克隆
- 亚 型： Rabbit Ig
- 抗体类型： 一抗
产品概览
| 背景： | CYP26A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues.REFERENCESQuere,R., Blood 109 (10), 4450-4460 (2007) Lee,S.J., Pharmacogenet. Genomics 17 (3), 169-180 (2007) Heise,R., J. Invest. Dermatol. 126 (11), 2473-2480 (2006) |
| 其他名字： | CYP26A1; CYP26; P450RAI1; Cytochrome P450 26A1; Cytochrome P450 retinoic acid-inactivating 1; Retinoic acid 4-hydroxylase; Retinoic acid-metabolizing cytochrome |
靶点信息
| 基因id： | 1592 |
| 蛋白名： | CYP26A1 |
| 胞内定位： | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein |
| 同义词： | CYP26, P450RAI1 |
应用与保存
| 稀释浓度： | WB~~1:1000WB~~1:1000IHC~~1:50~100FC~~1:10~50 |
| 注意事项： | CYP26A1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
其他
| 参考文献： | Quere,R., Blood 109 (10), 4450-4460 (2007) Lee,S.J., Pharmacogenet. Genomics 17 (3), 169-180 (2007) Heise,R., J. Invest. Dermatol. 126 (11), 2473-2480 (2006) |
| 保存条件： | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| 标记物： | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| 主要序列号： | O43174 |
| 其他序列号： | Q5VXI0 |
| 分子量： | 56199 Da |
| 功能： | Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18- hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA. |
| 规格： | 80 µl (8 western blots) | 价格： | ¥1100.00 |
| 规格： | 400 µl (40 western blots) | 价格： | ¥2310.00 |
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