efemp1多克隆抗体_货号：AP9095a-丁香通

EFEMP1 encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors.REFERENCESOkada,Y., et.al., Hum. Mol. Genet. (2010) In pressWakabayashi,T., et.al., Biochem. Biophys. Res. Commun. 391 (1), 1116-1121 (2010)

其他名字：

EFEMP1; FBLN3; FBNL; EGF-containing fibulin-like extracellular matrix protein 1; Extracellular protein S1-5; Fibrillin-like protein; Fibulin-3

产品特性

预测型适应物种：

Rat, Monkey

靶点信息

基因id：	2202
蛋白名：	EFEMP1
胞内定位：	Secreted, extracellular space (By similarity). Secreted, extracellular space, extracellular matrix (By similarity). Note=Localizes to the lamina propria underneath the olfactory epithelium (By similarity)
同义词：	FBLN3, FBNL

应用与保存

稀释浓度：	WB~~1:1000WB~~1:1000IHC~~1:50~100FC~~1:10~50
注意事项：	EFEMP1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.

其他

参考文献：	Okada,Y., et.al., Hum. Mol. Genet. (2010) In pressWakabayashi,T., et.al., Biochem. Biophys. Res. Commun. 391 (1), 1116-1121 (2010)
保存条件：	Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
标记物：	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
主要序列号：	Q12805
其他序列号：	O35568,Q8BPB5,Q7YQD7
分子量：	54641 Da
功能：	Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.

规格：	400 µl (40 western blots)	价格：	¥2310.00
规格：	80 µl (8 western blots)	价格：	¥1100.00

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