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抗人eif5单克隆抗体

  • 参考价格: ¥3190.0
  • 品  牌: abgent
  • 货  号: AT1885a
  • 适应物种: 
  • 应用范围: 免疫荧光,免疫印迹
  • 克 隆 性: 单克隆
  • 亚  型: IgG1 kappa
  • 抗体类型: 一抗
  • 详细信息
  • 图片

产品概览

背景Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).REFERENCESGlobal, in vivo, and site-specific phosphorylation dynamics in signaling networks. Olsen JV, et al. Cell, 2006 Nov 3. PMID 17081983.The crystal structure of the carboxy-terminal domain of human translation initiation factor eIF5. Bieniossek C, et al. J Mol Biol, 2006 Jul 7. PMID 16781736.Structure of the eukaryotic initiation factor (eIF) 5 reveals a fold common to several translation factors. Conte MR, et al. Biochemistry, 2006 Apr 11. PMID 16584190.CK2 phosphorylation of eukaryotic translation initiation factor 5 potentiates cell cycle progression. Homma MK, et al. Proc Natl Acad Sci U S A, 2005 Oct 25. PMID 16227438.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
其他名字EIF5Aeukaryotic translation initiation factor 5
克隆名2E6-4C12

靶点信息

基因id1983

应用与保存

稀释浓度WB~~1:500~1000
注意事项EIF5 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.

其他

参考文献Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Olsen JV, et al. Cell, 2006 Nov 3. PMID 17081983.The crystal structure of the carboxy-terminal domain of human translation initiation factor eIF5. Bieniossek C, et al. J Mol Biol, 2006 Jul 7. PMID 16781736.Structure of the eukaryotic initiation factor (eIF) 5 reveals a fold common to several translation factors. Conte MR, et al. Biochemistry, 2006 Apr 11. PMID 16584190.CK2 phosphorylation of eukaryotic translation initiation factor 5 potentiates cell cycle progression. Homma MK, et al. Proc Natl Acad Sci U S A, 2005 Oct 25. PMID 16227438.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
保存条件Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
标记物Clear, colorless solution in phosphate buffered saline, pH 7.2 .
主要序列号P55010
分子量49223 Da
规格:100 µg价格:¥3190.00