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ell多克隆抗体
- 参考价格： ¥1100.0 - 2310.0
- 品 牌： abgent
- 货 号： AP9479b
- 适应物种： 人,小鼠
- 应用范围： 免疫印迹
- 克 隆 性： 多克隆
- 亚 型： Rabbit Ig
- 抗体类型： 一抗
产品概览
| 背景： | Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.REFERENCES?Zhou, J., et al. J. Biol. Chem. 284(28):19142-19152(2009)?Jiang, F., et al. Cancer Lett. 253(2):265-272(2007)?Matsuoka, S., et al. Science 316(5828):1160-1166(2007) |
| 其他名字： | ELL; C19orf17; RNA polymerase II elongation factor ELL; Eleven-nineteen lysine-rich leukemia protein |
靶点信息
| 基因id： | 8178 |
| 蛋白名： | ELL |
| 胞内定位： | Nucleus speckle. Nucleus, Cajal body. Note=Colocalizes with EAF2 to nuclear speckles. Also localized to Cajal (coiled) bodies |
| 同义词： | C19orf17 |
应用与保存
| 稀释浓度： | WB~~1:1000WB~~1:1000 |
| 注意事项： | ELL Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
其他
| 参考文献： | ?Zhou, J., et al. J. Biol. Chem. 284(28):19142-19152(2009)?Jiang, F., et al. Cancer Lett. 253(2):265-272(2007)?Matsuoka, S., et al. Science 316(5828):1160-1166(2007) |
| 保存条件： | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| 标记物： | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| 主要序列号： | P55199 |
| 分子量： | 68265 Da |
| 功能： | Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre- initiation complex and early elongation. |
| 规格： | 80 µl (8 western blots) | 价格： | ¥1100.00 |
| 规格： | 400 µl (40 western blots) | 价格： | ¥2310.00 |
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