IL-6，IL-1β，TNF-α，IL-17请问大神们这些炎症因子有无对应的aptamer？

有的，以下是一些相关的文献：

IL-6: “SPR biosensor based on aptamer for detection of human interleukin-6”（doi: 10.1007/s00604-019-3717-5）和“Selection and characterization of DNA aptamers targeting all human interleukin-6 variants”（doi: 10.1016/j.jim.2021.113924）。

IL-1β: “Rapid and Sensitive Detection of Interleukin-1β by Lateral Flow Aptasensor”（doi: 10.3390/s20133371）和“Label-free detection of interleukin-1β using G-quadruplex-based electrochemical aptamer sensor”（doi: 10.1016/j.bios.2017.12.045）。

TNF-α: “TNF-α binding aptamer generates inflammatory signal and affords prolonged release of drugs in vivo”（doi: 10.1038/ncomms15319）和“Sensitive detection of tumor necrosis factor-alpha in human serum using a quartz crystal microbalance immunosensor with an aptamer as the bioreceptor”（doi: 10.1016/j.aca.2018.06.058）。

IL-17: “Rapid, Sensitive, and Specific Detection of Interleukin-17A by Lateral Flow Assay with Aptamer-Mediated Signal Amplification”（doi: 10.1021/acs.analchem.8b01941）和“Selection and characterization of DNA aptamers targeting all human interleukin-17A variants”（doi: 10.1016/j.jim.2021.114004）。。

白介素有相应的白介素受体，肿瘤坏死因子有受体家族