• 我要登录|
  • 免费注册
    |
  • 我的丁香通
    • 企业机构:
    • 成为企业机构
    • 个人用户:
    • 个人中心
  • 移动端
    移动端
丁香通 logo丁香实验_LOGO
搜实验

    大家都在搜

      大家都在搜

        0 人通过求购买到了急需的产品
        免费发布求购
        发布求购
        点赞
        收藏
        wx-share
        分享

        Products of Arachidonic Acid Metabolism

        互联网

        570
        Segmentation of the nephron relative to transport mechanisms and secretory activity has been recognized for decades, beginning with the pioneering studies of Alfred Newton Richards (1 ). Nephron segmentation regarding transcellular sodium and water movement has been subjected to a “comprehensive analysis of sodium transporter and water-channel protein abundance along the renal tubule” by Knepper and Masilamani (2 ). This experimental approach, based on targeted proteomics, uses an “ensemble of rabbit polyclonal antibodies directed to the major sodium transporters and water channels expressed in each renal tubule segment.” It allows and facilitates characterization and analysis of tubular functional differences that define individual nephron segments. However, individual tubular segments can be further subdivided according to secretory activity and transport mechanisms as, for example, the proximal tubules which have three portions (S1 , S2 , S3 ) distinguished by morphological differences and exhibiting multiple segregated functions such as the organic and anion secretory system (3 ) housed primarily in the straight segment (S2 ), and angiotensin II (ANGII) regulated reabsorptive function, localized primarily in the first few mm of the proximal tubules S1 segment (4 ).
        ad image
        提问
        扫一扫
        丁香实验小程序二维码
        实验小助手
        丁香实验公众号二维码
        扫码领资料
        反馈
        TOP
        打开小程序