• 我要登录|
  • 免费注册
    |
  • 我的丁香通
    • 企业机构:
    • 成为企业机构
    • 个人用户:
    • 个人中心
  • 移动端
    移动端
丁香通 logo丁香实验_LOGO
搜实验

    大家都在搜

      大家都在搜

        0 人通过求购买到了急需的产品
        免费发布求购
        发布求购
        点赞
        收藏
        wx-share
        分享

        STEC as a Veterinary Problem: Diagnostics and Prophylaxis in Animals

        互联网

        467
        Shiga toxin-producing Escherichia coli (STEC) are important human pathogens causing severe clinical syndromes in a high percentage of infected individuals (see Chapter 1 ). Naturally acquired STEC infections have also been detected in a wide spectrum of animal species (cattle, sheep, goat, deer, moose, swine, horse, dog, cat, pigeon, chicken, turkey, gull) sometimes even with considerable prevalences (1–10). Several of these animal hosts, particularly ruminants, have been identified as major reservoires of STEC strains that are highly virulent in the human host (e.g., EHEC O157:H7). However, in contrast to the human host, most STEC infections of animals remain clinically inapparent. Even in ruminant species, where shedding rates of up to 88% have been reported (2), the clinical significance of STEC infections seems to be rather limited. A natural pathogenic role of STEC has been clearly identified in weaned piglets (edema disease [ED] E. coli enterotoxemia) (11), calves (watery to bloody diarrhea) (12,13), and greyhounds (cutaneous and renal glomerular vasculopathy of greyhounds [CRVG], “Alabama rot”) (14,15). However, histological and in vitro studies revealed that certain epithelial and/or endothelial cells are affected by shiga toxins even in animals appearing clinical healthy (16–18). Thus, the true health importance of STEC infections for animal hosts may be underestimated.
        ad image
        提问
        扫一扫
        丁香实验小程序二维码
        实验小助手
        丁香实验公众号二维码
        扫码领资料
        反馈
        TOP
        打开小程序