Production of Fluorous-Based Microarrays with Uncharged Carbohydrates
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Fluorous-based carbohydrate microarrays provide an alternative to traditional covalent microarray �platforms for probing protein–carbohydrate-binding interactions. The most studied plant lectin, concanavalin A (ConA), is known to bind to terminally α-linked mannose. In the studies presented, the binding of ConA with α-mannose is analyzed using a microarray formed on a fluorous-coated glass slide with the sugar containing a fluorous tag at the anomeric position.
