（请教）这两个序列有什么不同？

第一个：
LOCUS AY651315 1275 bp mRNA linear INV 22-AUG-2004
DEFINITION Plasmodium falciparum isolate 2300 putative chloroquine resistance
transporter (crt) mRNA, complete cds.
ACCESSION AY651315
VERSION AY651315.1 GI:51317937
KEYWORDS .
SOURCE Plasmodium falciparum (malaria parasite P. falciparum)
ORGANISM Plasmodium falciparum
Eukaryota; Alveolata; Apicomplexa; Haemosporida; Plasmodium.
REFERENCE 1 (bases 1 to 1275)
AUTHORS Johnson,D.J., Maguire,J.D., Baird,K.J. and Fidock,D.A.
TITLE Novel haplotypes of Plasmodium falciparum pfcrt and their role in
chloroqine resistance
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1275)
AUTHORS Johnson,D.J., Maguire,J.D., Baird,K.J. and Fidock,D.A.
TITLE Direct Submission
JOURNAL Submitted (11-JUN-2004) Microbiology & Immunology, Albert Einstein
College of Medicine, 1300 Morris Park Avenue, Forchheimer 403,
Bronx, NY 10461, USA
FEATURES Location/Qualifiers
source 1..1275
/organism="Plasmodium falciparum"
/mol_type="mRNA"
/isolate="2300"
/db_xref="taxon:5833"
gene 1..1275
/gene="crt"
CDS 1..1275
/gene="crt"
/note="PfCRT"
/codon_start=1
/product="putative chloroquine resistance transporter"
/protein_id="AAU00067.1"
/db_xref="GI:51317938"
/translation="MKFASKKNNQKNSSKNDERYRELDNLVQEGNGSRLGGGSCLGKC
AHVFKLIFKEIKDNIFIYILSIIYLSVCVIKTIFAKRTLNKIGNYSFVTSETHNFICM
IMFFIVYSLFGNKKGNSKERHRSFNLQFFAISMLDACSVILAFIGLTRTTGNIQSFVL
QLSIPINMFFCFLILRYRYHLYNYLGAVIIVVTIALVEMKLSFETQEENSIIFNLVLI
SSLIPVCFSNMTREIVFKKYKIDILRLNAMVSFFQLFTSCLILPVYTLPFLKELHLPY
NEIWTNIKNGFACLFLGRNTVVENCGLGMAKLCDDCDGAWKTFALFSFFSICDNLITS
YIIDKFSTMTYTIVSCIQGPAIAIAYYFKFLAGDVVIEPRLLDFVTLFGYLFGSIIYR
VGNIILERKKMRNEENEDSEGELTNVDSIITQ"
ORIGIN
1 atgaaattcg caagtaaaaa aaataatcaa aaaaattcaa gcaaaaatga cgagcgttat
61 agagaattag ataatttagt acaagaagga aatggctcac gtttaggtgg aggttcttgt
121 cttggtaaat gtgctcatgt gtttaaactt atttttaaag agattaagga taatattttt
181 atttatattt taagtattat ttatttaagt gtatgtgtaa ttaaaacaat ttttgctaaa
241 agaactttaa acaaaattgg taactatagt tttgtaacat ccgaaactca caactttatt
301 tgtatgatta tgttctttat tgtttattcc ttatttggaa ataaaaaggg aaattcaaaa
361 gaacgacacc gaagctttaa tttacaattt tttgctatat ccatgttaga tgcctgttca
421 gtcattttgg ccttcatagg tcttacaaga actactggaa atatccaatc atttgttctt
481 caattaagta ttcctattaa tatgttcttc tgctttttaa tattaagata tagatatcac
541 ttatacaatt atctcggagc agttattatt gttgtaacaa tagctcttgt agaaatgaaa
601 ttatcttttg aaacacaaga agaaaattct atcatattta atcttgtctt aattagttcc
661 ttaattcctg tatgcttttc aaacatgaca agggaaatag tttttaaaaa atataagatt
721 gacattttaa gattaaatgc tatggtatcc tttttccaat tgttcacttc ttgtcttata
781 ttacctgtat acacccttcc atttttaaaa gaacttcatt taccatataa tgaaatatgg
841 acaaatataa aaaatggttt cgcatgttta ttcttgggaa gaaacacagt cgtagagaat
901 tgtggtcttg gtatggctaa gttatgtgat gattgtgacg gagcatggaa aaccttcgca
961 ttgttttcct tctttagcat ttgtgataat ttaataacca gctatattat cgacaaattt
1021 tctaccatga catatactat tgttagttgt atacaaggtc cagcaatagc aattgcttat
1081 tactttaaat tcttagccgg tgatgttgta atagaaccaa gattattaga tttcgtaact
1141 ttgtttggct acctatttgg ttctataatt taccgtgtag gaaatattat cttagaaaga
1201 aaaaaaatga gaaatgaaga aaatgaagat tccgaaggag aattaaccaa cgtcgattca
1261 attattacac aataa