Transplantation into Neonatal Rat Brain as a Tool to Study Properties of Stem Cells

Development of the brain is a complex set of events beginning at the time that the fate of embryonic cells is decided. Once chosen, these cells proceed on their migratory track, which brings them to the brain regions in which they reside and settle down. Here, the cells differentiate into array of distinct cell types, and establish a network of functional connections. How these migrating cells find their home and the complexity of events underlying the determination of their phenotypic fate are only partially understood.