Glycoprotein Detection of 2-D Separated Proteins
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The profile of the two-dimensional (2-D) separation of the protein complement (proteome) of eukaryotic cells and tissues typically contains obvious “trains” of spots that differ in pI and/or apparent molecular mass. These are usually isoforms of the same protein and result from a variety of posttranslational modifications. There is growing evidence that alterations to the glycosylation of a protein can be correlated with developmental and pathological changes; these changes can be visualized on the 2-D separation by alterations in the pattern of these glycoprotein isoforms.
![2H-噻吩并[3，2-D][1，3]噁嗪-2，4(1H)-二酮，78756-28-2，≥97%，阿拉丁](https://img1.dxycdn.com/p/s14/2024/0619/923/2131019441498633081.jpg!wh200)
