• 我要登录|
  • 免费注册
    |
  • 我的丁香通
    • 企业机构:
    • 成为企业机构
    • 个人用户:
    • 个人中心
  • 移动端
    移动端
丁香通 logo丁香实验_LOGO
搜实验

    大家都在搜

      大家都在搜

        0 人通过求购买到了急需的产品
        免费发布求购
        发布求购
        点赞
        收藏
        wx-share
        分享

        【求助】Cross-presentation of cell是一类什么细胞

        丁香园论坛

        1581
        如题,看文献cross-presentation of cell,是指哪类细胞,和APCs(抗原提呈细胞)是什么关系?谢谢
        The term cross-presentation denotes the ability of certain antigen-presenting cells to take up, process and present extracellular antigens with MHC class I molecules to CD8 T cells (cytotoxic T cells). Cross-priming describes the stimulation of naive cytotoxic CD8+ T cells by this process[1]. This process is necessary for immunity against most tumors and against viruses that do not infect antigen-presenting cells.[2][3]
        详见:http://en.wikipedia.org/wiki/Cross-presentation
        Dendritic cell have the unique ability to capture extracellular antigen and load to MHC1 then cross prime CD8 T cell. it was reported that some other cells such as macrophage and some endothelial cell in specific tissue have this ability as well.
        I remember a paper reported that macrophage infected with bacterial such as mycobacteria can present bacterial antigen to MHC2 and prime CD8 T cell which represent a detour antigen presentation pathway. I am not sure if this is another kind of cross presentation.

        本文由丁香园论坛提供,想了解更多有用的、有意思的前沿资讯以及酷炫的实验方法的你,都可以成为师兄的好伙伴

        师兄微信号:shixiongcoming

        ad image
        提问
        扫一扫
        丁香实验小程序二维码
        实验小助手
        丁香实验公众号二维码
        扫码领资料
        反馈
        TOP
        打开小程序