Lyophilization of Nonviral Gene Delivery Systems
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This chapter presents a qualitative description of the freeze-drying process as it pertains to the development of stable, dry polycation-DNA complex formulations. It is not intended to be a comprehensive treatise on freeze-drying. Readers are referred to a series of excellent papers by Pikal (1 –5 ) for more detailed, quantitative explanations of the freeze-drying process.
