【进展|热点】分享参加6th International Symposium on CD1 and NKT Cells后的感想
丁香园论坛
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如题，
感觉级别挺很高的,据说Nature immunol.之后都会有简短综述报道
http://www.certain.com/system/profile/web/index.cfm?PKwebID=0x2186723327&varPage=home
PROGRAM & SPEAKERS
Click here to download and view/print the complete symposium program schedule!
<center> <span><strong>ARRIVAL DAY - SEPTEMBER 23, 2011 (FRIDAY) 7:00 PM - 8:00 PM</strong></span></center> <center> <em>Welcome Reception 6:00 PM-7:00 PM: Sheraton Chicago Hotel & Towers</em></center> <center> <em>Keynote Lecture 7:00 PM-8:00 PM: </em><strong>Michael Brenner, </strong>Harvard Medical School, USA</center> <center> <em>Potent self-antigens enable invariant NKT TCRs to interpret microbial danger signals</em></center> <center> </center> <center> </center> <center> <span><strong>DAY 1 - SEPTEMBER 24, 2011 (SATURDAY)</strong></span></center>
Morning Session (8:00 AM - 12:00 PM):
NKT Cells: Development and Homeostasis, Chairs: Albert Bendelac & Dale Godfrey
Albert Bendelac, University of Chicago, USA
Coordinated Induction of Egr2 and PLZF Controls NKT Lineage Development
Giulia Casorati, Foundation San Raffaele, Italy (Short Talk)
Mechanism controlling iNKT cell functional development
Mihalis Verykokakis, University of Chicago, USA (Short Talk)
Role of Id3 in Thymic NKT Cell Maturation
J. Christoph Vahl, Max Plank Institute Martinsried, Germany (Short Talk)
Probing Valpha1 4i-inherent autoreactivity by a peripheral TCR switch
Sebastian Joyce, Vanderbilt University, USA
Thymic Selection of NKT Cells
Alan Baxter, James Cook University, Australia (Short Talk)
Role of Peroxisomes in NKT Cell Biology
Coffee Break
Dale Godfrey, University of Melbourne, Australia
Variations in 'Invariant' NKT Cells
Masaru Taniguchi, Riken Research Center for Allergy and Immunology, Japan
Early NKT Precursor
Kristin Hogquist, University of Minnesota, USA
Crosstalk Between NKT and Conventional T Cells
H. Robson MacDonald, Ludwig Institute for Cancer Research, Switzerland
Ly-49 Inhibitory Receptors Shape the Vbeta Repertoire of Developing Invariant NKT Cells
Afternoon Session (2:00 PM - 5:30 PM):
Structure; Antigen Processing and Presentation, Chairs: Erin Adams & Randy Brutkiewicz
Randy Brutkiewicz, Indiana University, USA
Cell Signaling Pathways that Control CD1d-Mediated Antigen Presentation
Markus Moll, Karolinska Institute, Sweden (Short Talk)
Viral interference with CD1-restricted immunity
Peter Cresswell, Yale University, USA
Lysophospholipids and CD1d recognition by NKT cells
Gennaro De Libero, University of Basel, Switzerland
Regulation of Lipid Antigen Presentation
Martine Gilleron, Universite de Toulouse, France (Short Talk)
Role of CD1e and Lipases in the Processing of Multi-Acylated Mycobacterial Lipid Antigens
Coffee Break
Erin Adams, University of Chicago, USA
The Molecular Recognition of CD1d Presented Lysophospholipids by NKT Cells
Jamie Rossjohn, Monash University, Australia
NKT TCR Recognition of CD1d-restricted Ags
Laurent Gapin, University of Colorado USA
TCR-Ligand Affinity in NKT Development
Dirk Zajonc, La Jolla Institute for Allergy and Immunology, USA
Structural Basis of Microbial Lipid Recognition
Poster Session I (5:30 PM - 7:30 PM)
<center> <span><strong>DAY 2 - SEPTEMBER 25, 2011 (SUNDAY)</strong></span></center>
Morning Session (8:00 AM - 12:00 PM):
Effector Function/Immunoregulation by NKT Cell Subsets, Chairs: Masaru Taniguchi & Chyung-Ru Wang
Kim Nichols, Children's Hospital of Philadelphia, USA (Short Talk)
Conditional Elimination of SAP Reveals Selective Roles in Natural Killer T Cell Function
Toshinori Nakayama, Chiba University, Japan
NKT Cell-Mediated Regulation of Antigen-Specific Memory Th2 Cell Function
Hiroshi Watarai, Riken Research Center for Allergy and Immunology, Japan (Short Talk)
Development and Function of invariant NKT cells Producing Th2 and Th17 Cytokines
Kamel Benlagha, INSERM, France
Innate IL-17 Response of PLN NK1.T iNKT Cells to Bacteria
Jenny Gumperz, University of Wisconsin, USA
Immunoregulation by Human NKT Cells
Coffee Break
Chyung-Ru Wang, Northwestern University, USA
Group 1 CD1 in T Cell Development and Anti-Microbial Immunity
Christian Kurts, Institute of Molecular Medicine and Experimental Immunology, Germany
NKT Cell-Mediated Lincensing of DCs for Cross-Priming
Elizabeth Leadbetter, Trudeau Institute, USA (Short Talk)
Visualizing the Splenic iNKT Cell Effector Program: Cross-Talk with DCs at the Marginal Zone
Stephane Gerart, Hopital Necker Enfants-Malades, France (Short Talk)
High Suceptibility of Invariant NKT cells to Apoptosis Is Controlled by XIAP
Luc Van Kaer, Vanderbilt University, USA
NKT Cell Activation and Anergy
Afternoon Session (2:00 PM - 5:30 PM):
Ligands and Vaccines, Chairs: Steve Porcelli & Facundo Batista
Steve Porcelli, Albert Einstein College of Medicine, USA
Structure-Activity Relationships of NKT Cell Ligands and their Use as Vaccine Adjuvants
Li Bai, University of Science and Technology, China (Short Talk)
Distinct Antigen-Presenting Cells Explain the Cytokine Bias of aGC Variants In Vivo
Moriya Tsuji, Aaron Diamond AIDS Research Center, USA
Clinical Development of a Novel CD1d-Binding NKT Cell Ligand as an Adjuvant
Luc Teyton, Scripps Research Institute, USA
Transport and Uptake of NKT Ligands
Alena Donda, University of Lausanne, Switzerland (Short Talk)
CD1d-Antitumor scFv Fusion Proteins Induce Efficient Tumor Cell Killing
Coffee Break
Facundo Batista, London Research Institute, UK
Understanding how iNKTs Potentiate Specific Antibody Responses in vivo
Paul Savage, Brigham Young University, USA (Short Talk)
NKT Cell Adjuvants For Oligosaccharide Vaccines
Dapeng Zhou, MD Anderson, USA
Nanoparticle Delivery of NKT Ligands for Immunotherapy and Vaccines
Dirk Elewaut, Ghent University, Belgium
Galactose-Modified iNKT Cell Agonists Stabilized by an Induced Fit of CD1d Prevent Metastasis
Poster Session II (5:30 PM - 7:30 PM)
<center> <span><strong>DAY 3 - SEPTEMBER 26, 2011 (MONDAY)</strong></span></center>
Morning Session (8:00 AM - 12:00 PM):
Microbial Immunity, Chairs: Mitchell Kronenberg & Branch Moody
Mitchell Kronenberg, La Jolla Institute for Allergy and Immunology, USA
Microbial NKT Ligands
Florian Winau, Harvard Medical School, USA
NKT Cell Activation by Self
Paul Kubes, University of Calgary, Canada
Intravital Imaging of the NKT Response to Infection and Sterile Injury
Claire Forestier, INSERM, France (Short Talk)
Distinct iNKT cell Responses to Leishmania Parasites In Acute or Silent Visceral Leishmaniasis
Shailbala Singh, MD Anderson, USA (Short Talk)
Mucosal aGC Delivery Overcomes NKT Cell Anergy to Enable Priming and Boosting of Adaptive
Responses
Coffee Break
Branch Moody, Harvard Medical School, USA
New Mycobacterial Lipid Antigens that Activate Human T Cells in vitro and ex vivo
Chetan Seshadri, University of Washington, USA (Short Talk)
Human CD1A-deficiency is Associated with Susceptibility to Mycobacterial Disease
Olivier Lantz, Institut Curie, France
MAIT cells, a Conserved T-cell Subset with Anti-Microbial Activity
Rick Blumberg, Harvard Medical School, USA
Mechanisms of NKT Cell Mediated Regulation of Intestinal Inflammation
Sebastian Zeissig, Harvard Medical School, USA (Short Talk)
HBV Infection Alters Endogenous CD1d Antigens Leading to NKT Activation and Viral Clearance
Luncheon Session (12:30 PM - 1:30 PM):
Biotechnologies, Chair: Moriya Tsuji
Vincent Serra, CEO CSO, Wittycell
Novel Vaccine Adjuvants for Induction of Cellular and Humoral Immunity
Maurice Zauderer, President & CEO, Vaccinex, Inc.
NKT Cell based Therapeutic Strategies
Alem Truneh, Co-founder & CSO, NKT Therapeutics, Inc.
Development of First-In-Class Antibodies Targeting iNKT Cells for Treatment of Inflammatory Diseases and Cancer
Afternoon Group Activity: 3:00PM - 4:30PM, Chicago River Boat Architecture Tour
EVENING GALA DINNER: 6:00PM - 9:00PM, The Modern Wing, The Art Institute of Chicago
<center> <strong><span>DAY 4 - SEPTEMBER 27, 2011 (TUESDAY</span></strong>)</center> <center> </center> <center> </center>
Morning Session (8:00 AM - 12:00 PM):
Autoimmune Diseases, Inflammation and Cancer, Chairs: Agnes Lehuen & Vincenzo Cerundolo
Vincenzo Cerundolo, University of Oxford, UK
NKT Suppression vs Activation in Infection and Cancer
Paolo Dellabona, Foundation San Raffaele, Italy
The CD1/T Cell Axis in Leukaemia Immune Surveillance
Fred Finkelman, University of Cincinnati, USA (Short Talk)
When and Why Are NKT Cells Required for Development of Airway Hyperresponsiveness
Gerhard Wingender, La Jolla Institute for Allergy and Immunology, USA (Short Talk)
Environmental Antigens for Invariant NKT cells and their Role in Airway Inflammation
Hye-Young Kim, Harvard Medical School, USA (Short Talk)
Innate Lymphoid Cells Responding to IL-33 Mediate Airway Hyperreactivity
Lydia Lynch, Harvard Medical School, USA (Short Talk)
Unique iNKT Cells are Enriched in Fat, and Protect Against Obesity-Induced Metabolic Disorder
Coffee Break
Agnes Lehuen, INSERM U561, France
Regulatory Role of NKT Cells: from Viral Infection to Type 1 Diabetes
Mikael Karlsson, Karolinska Institute, Sweden
NKT Cells in Innate B Cell Activation
Jochen Mattner, Cincinnati Children's Hospital Medical Center, USA
Genetic Susceptibility to Infection-Induced Liver Autoimmunity
Maria Leite-de-Moraes, CNRS, France (Short Talk)
Donor-Derived Invariant NKT cell Recovery Inversely Correlates with Acute GVHD
Shinichiro Motohashi, Chiba University, Japan (Short Talk)
NKT Cell-Based Immunotherapy For Non-Small Cell Lung Cancer
DEPARTURE - SEPTEMBER 27, 2011 (TUESDAY) NOON
感觉级别挺很高的,据说Nature immunol.之后都会有简短综述报道
http://www.certain.com/system/profile/web/index.cfm?PKwebID=0x2186723327&varPage=home
PROGRAM & SPEAKERS
Click here to download and view/print the complete symposium program schedule!
<center> <span><strong>ARRIVAL DAY - SEPTEMBER 23, 2011 (FRIDAY) 7:00 PM - 8:00 PM</strong></span></center> <center> <em>Welcome Reception 6:00 PM-7:00 PM: Sheraton Chicago Hotel & Towers</em></center> <center> <em>Keynote Lecture 7:00 PM-8:00 PM: </em><strong>Michael Brenner, </strong>Harvard Medical School, USA</center> <center> <em>Potent self-antigens enable invariant NKT TCRs to interpret microbial danger signals</em></center> <center> </center> <center> </center> <center> <span><strong>DAY 1 - SEPTEMBER 24, 2011 (SATURDAY)</strong></span></center>
Morning Session (8:00 AM - 12:00 PM):
NKT Cells: Development and Homeostasis, Chairs: Albert Bendelac & Dale Godfrey
Albert Bendelac, University of Chicago, USA
Coordinated Induction of Egr2 and PLZF Controls NKT Lineage Development
Giulia Casorati, Foundation San Raffaele, Italy (Short Talk)
Mechanism controlling iNKT cell functional development
Mihalis Verykokakis, University of Chicago, USA (Short Talk)
Role of Id3 in Thymic NKT Cell Maturation
J. Christoph Vahl, Max Plank Institute Martinsried, Germany (Short Talk)
Probing Valpha1 4i-inherent autoreactivity by a peripheral TCR switch
Sebastian Joyce, Vanderbilt University, USA
Thymic Selection of NKT Cells
Alan Baxter, James Cook University, Australia (Short Talk)
Role of Peroxisomes in NKT Cell Biology
Coffee Break
Dale Godfrey, University of Melbourne, Australia
Variations in 'Invariant' NKT Cells
Masaru Taniguchi, Riken Research Center for Allergy and Immunology, Japan
Early NKT Precursor
Kristin Hogquist, University of Minnesota, USA
Crosstalk Between NKT and Conventional T Cells
H. Robson MacDonald, Ludwig Institute for Cancer Research, Switzerland
Ly-49 Inhibitory Receptors Shape the Vbeta Repertoire of Developing Invariant NKT Cells
Afternoon Session (2:00 PM - 5:30 PM):
Structure; Antigen Processing and Presentation, Chairs: Erin Adams & Randy Brutkiewicz
Randy Brutkiewicz, Indiana University, USA
Cell Signaling Pathways that Control CD1d-Mediated Antigen Presentation
Markus Moll, Karolinska Institute, Sweden (Short Talk)
Viral interference with CD1-restricted immunity
Peter Cresswell, Yale University, USA
Lysophospholipids and CD1d recognition by NKT cells
Gennaro De Libero, University of Basel, Switzerland
Regulation of Lipid Antigen Presentation
Martine Gilleron, Universite de Toulouse, France (Short Talk)
Role of CD1e and Lipases in the Processing of Multi-Acylated Mycobacterial Lipid Antigens
Coffee Break
Erin Adams, University of Chicago, USA
The Molecular Recognition of CD1d Presented Lysophospholipids by NKT Cells
Jamie Rossjohn, Monash University, Australia
NKT TCR Recognition of CD1d-restricted Ags
Laurent Gapin, University of Colorado USA
TCR-Ligand Affinity in NKT Development
Dirk Zajonc, La Jolla Institute for Allergy and Immunology, USA
Structural Basis of Microbial Lipid Recognition
Poster Session I (5:30 PM - 7:30 PM)
<center> <span><strong>DAY 2 - SEPTEMBER 25, 2011 (SUNDAY)</strong></span></center>
Morning Session (8:00 AM - 12:00 PM):
Effector Function/Immunoregulation by NKT Cell Subsets, Chairs: Masaru Taniguchi & Chyung-Ru Wang
Kim Nichols, Children's Hospital of Philadelphia, USA (Short Talk)
Conditional Elimination of SAP Reveals Selective Roles in Natural Killer T Cell Function
Toshinori Nakayama, Chiba University, Japan
NKT Cell-Mediated Regulation of Antigen-Specific Memory Th2 Cell Function
Hiroshi Watarai, Riken Research Center for Allergy and Immunology, Japan (Short Talk)
Development and Function of invariant NKT cells Producing Th2 and Th17 Cytokines
Kamel Benlagha, INSERM, France
Innate IL-17 Response of PLN NK1.T iNKT Cells to Bacteria
Jenny Gumperz, University of Wisconsin, USA
Immunoregulation by Human NKT Cells
Coffee Break
Chyung-Ru Wang, Northwestern University, USA
Group 1 CD1 in T Cell Development and Anti-Microbial Immunity
Christian Kurts, Institute of Molecular Medicine and Experimental Immunology, Germany
NKT Cell-Mediated Lincensing of DCs for Cross-Priming
Elizabeth Leadbetter, Trudeau Institute, USA (Short Talk)
Visualizing the Splenic iNKT Cell Effector Program: Cross-Talk with DCs at the Marginal Zone
Stephane Gerart, Hopital Necker Enfants-Malades, France (Short Talk)
High Suceptibility of Invariant NKT cells to Apoptosis Is Controlled by XIAP
Luc Van Kaer, Vanderbilt University, USA
NKT Cell Activation and Anergy
Afternoon Session (2:00 PM - 5:30 PM):
Ligands and Vaccines, Chairs: Steve Porcelli & Facundo Batista
Steve Porcelli, Albert Einstein College of Medicine, USA
Structure-Activity Relationships of NKT Cell Ligands and their Use as Vaccine Adjuvants
Li Bai, University of Science and Technology, China (Short Talk)
Distinct Antigen-Presenting Cells Explain the Cytokine Bias of aGC Variants In Vivo
Moriya Tsuji, Aaron Diamond AIDS Research Center, USA
Clinical Development of a Novel CD1d-Binding NKT Cell Ligand as an Adjuvant
Luc Teyton, Scripps Research Institute, USA
Transport and Uptake of NKT Ligands
Alena Donda, University of Lausanne, Switzerland (Short Talk)
CD1d-Antitumor scFv Fusion Proteins Induce Efficient Tumor Cell Killing
Coffee Break
Facundo Batista, London Research Institute, UK
Understanding how iNKTs Potentiate Specific Antibody Responses in vivo
Paul Savage, Brigham Young University, USA (Short Talk)
NKT Cell Adjuvants For Oligosaccharide Vaccines
Dapeng Zhou, MD Anderson, USA
Nanoparticle Delivery of NKT Ligands for Immunotherapy and Vaccines
Dirk Elewaut, Ghent University, Belgium
Galactose-Modified iNKT Cell Agonists Stabilized by an Induced Fit of CD1d Prevent Metastasis
Poster Session II (5:30 PM - 7:30 PM)
<center> <span><strong>DAY 3 - SEPTEMBER 26, 2011 (MONDAY)</strong></span></center>
Morning Session (8:00 AM - 12:00 PM):
Microbial Immunity, Chairs: Mitchell Kronenberg & Branch Moody
Mitchell Kronenberg, La Jolla Institute for Allergy and Immunology, USA
Microbial NKT Ligands
Florian Winau, Harvard Medical School, USA
NKT Cell Activation by Self
Paul Kubes, University of Calgary, Canada
Intravital Imaging of the NKT Response to Infection and Sterile Injury
Claire Forestier, INSERM, France (Short Talk)
Distinct iNKT cell Responses to Leishmania Parasites In Acute or Silent Visceral Leishmaniasis
Shailbala Singh, MD Anderson, USA (Short Talk)
Mucosal aGC Delivery Overcomes NKT Cell Anergy to Enable Priming and Boosting of Adaptive
Responses
Coffee Break
Branch Moody, Harvard Medical School, USA
New Mycobacterial Lipid Antigens that Activate Human T Cells in vitro and ex vivo
Chetan Seshadri, University of Washington, USA (Short Talk)
Human CD1A-deficiency is Associated with Susceptibility to Mycobacterial Disease
Olivier Lantz, Institut Curie, France
MAIT cells, a Conserved T-cell Subset with Anti-Microbial Activity
Rick Blumberg, Harvard Medical School, USA
Mechanisms of NKT Cell Mediated Regulation of Intestinal Inflammation
Sebastian Zeissig, Harvard Medical School, USA (Short Talk)
HBV Infection Alters Endogenous CD1d Antigens Leading to NKT Activation and Viral Clearance
Luncheon Session (12:30 PM - 1:30 PM):
Biotechnologies, Chair: Moriya Tsuji
Vincent Serra, CEO CSO, Wittycell
Novel Vaccine Adjuvants for Induction of Cellular and Humoral Immunity
Maurice Zauderer, President & CEO, Vaccinex, Inc.
NKT Cell based Therapeutic Strategies
Alem Truneh, Co-founder & CSO, NKT Therapeutics, Inc.
Development of First-In-Class Antibodies Targeting iNKT Cells for Treatment of Inflammatory Diseases and Cancer
Afternoon Group Activity: 3:00PM - 4:30PM, Chicago River Boat Architecture Tour
EVENING GALA DINNER: 6:00PM - 9:00PM, The Modern Wing, The Art Institute of Chicago
<center> <strong><span>DAY 4 - SEPTEMBER 27, 2011 (TUESDAY</span></strong>)</center> <center> </center> <center> </center>
Morning Session (8:00 AM - 12:00 PM):
Autoimmune Diseases, Inflammation and Cancer, Chairs: Agnes Lehuen & Vincenzo Cerundolo
Vincenzo Cerundolo, University of Oxford, UK
NKT Suppression vs Activation in Infection and Cancer
Paolo Dellabona, Foundation San Raffaele, Italy
The CD1/T Cell Axis in Leukaemia Immune Surveillance
Fred Finkelman, University of Cincinnati, USA (Short Talk)
When and Why Are NKT Cells Required for Development of Airway Hyperresponsiveness
Gerhard Wingender, La Jolla Institute for Allergy and Immunology, USA (Short Talk)
Environmental Antigens for Invariant NKT cells and their Role in Airway Inflammation
Hye-Young Kim, Harvard Medical School, USA (Short Talk)
Innate Lymphoid Cells Responding to IL-33 Mediate Airway Hyperreactivity
Lydia Lynch, Harvard Medical School, USA (Short Talk)
Unique iNKT Cells are Enriched in Fat, and Protect Against Obesity-Induced Metabolic Disorder
Coffee Break
Agnes Lehuen, INSERM U561, France
Regulatory Role of NKT Cells: from Viral Infection to Type 1 Diabetes
Mikael Karlsson, Karolinska Institute, Sweden
NKT Cells in Innate B Cell Activation
Jochen Mattner, Cincinnati Children's Hospital Medical Center, USA
Genetic Susceptibility to Infection-Induced Liver Autoimmunity
Maria Leite-de-Moraes, CNRS, France (Short Talk)
Donor-Derived Invariant NKT cell Recovery Inversely Correlates with Acute GVHD
Shinichiro Motohashi, Chiba University, Japan (Short Talk)
NKT Cell-Based Immunotherapy For Non-Small Cell Lung Cancer
DEPARTURE - SEPTEMBER 27, 2011 (TUESDAY) NOON
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